ArticleEuropean heart journal. Case reports2025
Rescue catheter directed treatment for floating right atrial thrombi and deep vein thrombosis in patient with high-risk acute pulmonary embolism: a case report of multidisciplinary approach.
Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: High-risk pulmonary embolism (PE) complicated by floating right atrial thrombi (RAT) carries a significantly increased mortality risk, often requiring urgent intervention beyond systemic thrombolysis (ST). However, current guidelines lack specific recommendations for managing persistent RAT following ST. Catheter-directed therapies (CDTs) have emerged as a promising alternative in this setting. We report a novel single-session, multidisciplinary approach combining mechanical thrombectomy of both RAT and iliofemoral deep vein thrombosis (DVT) using the Penumbra Indigo Lightning System. Case summary: A 74-year-old woman presented with syncope and signs of cardiogenic shock. Imaging confirmed high-risk PE with floating RAT and extensive iliofemoral DVT. Initial treatment with ST led to partial haemodynamic recovery but persistent RAT. A multidisciplinary Pulmonary Embolism Response Team elected to perform percutaneous thrombectomy. Under transoesophageal echocardiography and fluoroscopic guidance, mechanical aspiration of the right atrial thrombus was successfully performed using the Penumbra Indigo Lightning 12 F catheter. In the same session, intravascular ultrasound-guided aspiration of iliofemoral DVT was achieved, with confirmation of complete thrombus removal and exclusion of the May-Thurner syndrome. The patient had an uneventful recovery, with restored right ventricular function and no recurrent thromboembolism or post-thrombotic syndrome at follow-up. Discussion: This case demonstrates the feasibility and safety of a combined single-session catheter-directed approach for simultaneous treatment of RAT and DVT following ST failure. The integration of multidisciplinary decision-making, advanced aspiration technology, and intravascular imaging may optimize outcomes in complex PE cases and supports expanding the role of CDTs in rescue settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.