ArticleEuropean heart journal. Case reports2025
One-stop strategy combining pulmonary vein isolation with balloon-in-basket pulsed field ablation and left atrial appendage closure: a case report.
Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- COnCOmitaNt pulsed field ablation-based pUlmonary vein isolation and lefT atrial appendage closure: the COCONUT study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
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5 authors.
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Abstract
Background: Concomitant pulmonary vein isolation (PVI) and left atrial appendage closure (LAAC) are increasingly performed, with substantial experience from thermal ablation and limited early reports using pulsed field ablation (PFA). This is the first reported case of a combined procedure using a balloon-in-basket PFA system. Case summary: A 75-year-old man with symptomatic paroxysmal atrial fibrillation (AF) and recurrent macrohematuria under oral anticoagulation was referred for treatment. After a multidisciplinary team discussion, we opted for a one-stop approach combining PVI using a balloon-in-basket PFA system and LAAC. The procedure proceeded without complications, and at the end of the procedure and in follow-up imaging, no residual leak was detected. Discussion: This case highlights the feasibility of combining balloon-in-basket based PFA with LAAC in a single procedure. Performing ablation prior to LAAC may help avoid potential interactions between the ablation catheter and the occlusion device, while careful procedural planning can ensure optimal device sizing and complete sealing of the appendage, even in the context of post-ablation tissue changes.
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