Evidence map›Paper›PMID 41424245›Full record

ArticleeLife2025

Structural basis for collagen recognition by the

Marta Wojnowska, Takeaki Wajima, Tamas Yelland, Hannes Ludewig, Robert M Hagan, Olivia F McCurry, Grant Watt, Samir W Hamaia, Dominique Bihan, Jean-Daniel Malcor and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Marta Wojnowska *School of Biology, Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, United Kingdom.ORCID https://orcid.org/0000-0001-8954-5127
Takeaki Wajima *Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-9506-707X
Tamas YellandCRUK Beatson Institute, Glasgow, United Kingdom.
Hannes LudewigSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, United Kingdom.ORCID https://orcid.org/0000-0003-1130-1442
Robert M HaganSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, United Kingdom.
Olivia F McCurrySchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, United Kingdom.ORCID https://orcid.org/0009-0002-0372-0137
Grant WattSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, United Kingdom.
Samir W HamaiaDepartment of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom.
Dominique BihanDepartment of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom.
Jean-Daniel MalcorDepartment of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0003-4208-1294
Arkadiusz BonnaDepartment of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom.
Helena BergstenCenter for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Laura Marcela Palma MedinaCenter for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-4049-9622
Mattias SvenssonCenter for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-1695-7934
Oddvar OppegaardDepartment of Medicine, Haukeland University Hospital, Bergen, Norway.
Steinar SkredeDepartment of Medicine, Haukeland University Hospital, Bergen, Norway.
Per ArnellDepartment of Anesthesiology and Intensive Care Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Ole HyldegaardDepartment of Anesthesiology, Hyperbaric Medicine Center, Head and Orthopedic Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Richard W FarndaleDepartment of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom.
Anna Norrby-Teglund *Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-9372-1795
Ulrich Schwarz-Linek *School of Biology, Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, United Kingdom.ORCID https://orcid.org/0000-0003-0526-223X

Funding

British Heart Foundation RG/09/003/27122British Heart Foundation RG/15/4/31268British Heart Foundation SP/15/7/31561Center for Innovative Medicine FoUI-975603European Commission FP6 ASSIST (032390)European Commission FP7 INFECT (305340)Medical Research Council MR/N009681/1Vetenskapsrådet 2022-01-202
6 · The paper itself

Abstract

The M protein is an essential virulence factor of

Indexed as

Antigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsBiofilmsCarrier ProteinsCollagenStreptococcus pyogenesHumansModels, MolecularProtein BindingStreptococcal InfectionsVirulence FactorsAntigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsCarrier ProteinsCollagenstreptococcal M proteinVirulence Factorsbacterial adhesionbiofilmcollagenE. colihumaninfectious diseasemicrobiologymolecular biophysicsprotein structureS. pyogenesstreptococcal M proteinsstructural biology

Identifiers

PMID41424245
PMCPMC12721709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.