Evidence map›Paper›PMID 41424131›Full record

ArticleBJPsych open2025

Longitudinal validation of the Maudsley 3-item visual analogue scale (M3VAS): a new, brief, patient-reported outcome measure of depression.

Daniel Silman, Maria Elena Middag, Anthony J Cleare, Allan H Young, Rebecca Strawbridge

Registry-linked trialAbstract read
In one paragraph

Article in BJPsych open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04939818 (A Study to Investigate the Feasibility of Administration of a Speech Battery and the Use of Speech-based Biomarkers for the Clinical Assessment of Common Neurodegenerative and Psychiatric Disorders in a Remote Setting.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04939818 completednot on this map

A Study to Investigate the Feasibility of Administration of a Speech Battery and the Use of Speech-based Biomarkers for the Clinical Assessment of Common Neurodegenerative and Psychiatric Disorders in a Remote Setting.

Typeobservational_patient_registrySponsorNovoic LimitedRan2021 to 2022Enrolled172ConditionsAlzheimer Disease, Mild Cognitive Impairment, Dementia With Lewy Bodies, Dementia, Vascular
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel SilmanCentre for Affective Disorders, Department of Psychological Medicine, https://ror.org/0220mzb33Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0001-9069-6395
Maria Elena MiddagCentre for Affective Disorders, Department of Psychological Medicine, https://ror.org/0220mzb33Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Anthony J CleareCentre for Affective Disorders, Department of Psychological Medicine, https://ror.org/0220mzb33Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Allan H YoungCentre for Affective Disorders, Department of Psychological Medicine, https://ror.org/0220mzb33Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0003-2291-6952
Rebecca StrawbridgeCentre for Affective Disorders, Department of Psychological Medicine, https://ror.org/0220mzb33Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0002-2984-1124

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Maudsley 3-item visual analogue scale (M3VAS) was developed as a novel and intuitive patient-reported measure for depression, focusing on core symptoms and suicidality.

aimsTo evaluate the longitudinal validity of M3VAS for capturing symptom change over time.

methodBoth M3VAS and the Patient Health Questionnaire (PHQ-9, as reference standard) were administered in an observational study (RHAPSODY, no. NCT04939818) at weeks 0, 2 and 4 to both depressed patients (

resultsM3VAS exhibited strong factor loadings and high item interrelatedness (Cronbach's alpha 0.78-0.83) at all time points. Total scores correlated strongly with PHQ-9 at each time point (

conclusionsFollowing previous cross-sectional validation against the Quick Inventory of Depressive Symptomatology-Self-report, this present study demonstrated appropriate longitudinal measurement properties for M3VAS as a measure of depression, including responsiveness. Evaluating the ability of M3VAS to discern responses with a variety of treatments is a key future goal.

Indexed as

Antidepressantsbipolar type I or II disordersdepressive disordersdiagnosis and classificationmood stabilisers

Identifiers

PMID41424131
PMCPMC12724119

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.