Evidence map›Paper›PMID 41423702›Full record

ReviewJournal of cardiovascular electrophysiology2026

Understanding Atrial Fibrillation Complexity Through the Lens of Turbulence Dynamics: Implications for Treatment Strategies.

Xin Chu, Xiaohan Jiang, Qing Qiao, Xiaojun Wang, Hong Ye

Abstract readReview
In one paragraph

Review in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xin ChuDepartment of Cardiovascular Medicine, Anhui Chest Hospital, Hefei, Anhui, China.ORCID 0009-0006-7665-9241
Xiaohan JiangAnhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.ORCID 0000-0002-7872-2703
Qing QiaoDepartment of Cardiovascular Medicine, Anhui Chest Hospital, Hefei, Anhui, China.
Xiaojun WangDepartment of Cardiovascular Medicine, Anhui Chest Hospital, Hefei, Anhui, China.
Hong YeDepartment of Cardiovascular Medicine, Anhui Chest Hospital, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. Its incidence increases significantly with age and has become a major global public health issue. Although research into the mechanisms of AF has spanned over a century-ranging from the reentry theory to the rotor hypothesis-none of these theories can fully explain its complex dynamic characteristics. The electrical activity of AF exhibits similarities to fluid turbulence, and this analogy provides a new theoretical framework for understanding AF. This review systematically outlines the evolution of AF theories and analyzes the multidimensional connections between the electrophysiological properties of atrial myocardium and the principles of turbulence dynamics. These include the nonlinear propagation characteristics of electrical wavefronts, the impact of atrial tissue heterogeneity on wave conduction, and the therapeutic rationale of catheter ablation targeting the sources of turbulence. Based on this, the study proposes the hypothesis that cardiac electrical activity in AF resembles a turbulence-like state, suggesting that AF fundamentally represents a nonlinear dynamic turbulence-like phenomenon of myocardial excitation waves under certain conditions. This hypothesis posits that critical arrhythmogenic substrates in AF-characterized by established structural and electrophysiological heterogeneities-create conditions analogous to sites where turbulence dynamics emerge in fluid systems, providing a phenomenological framework for characterizing the spatial-temporal organization underlying ablation therapy efficacy. By integrating traditional AF theories with fluid dynamics concepts of turbulence, this hypothesis holds promise for more comprehensively explaining the complex characteristics and individual variability of AF, thereby offering a new theoretical foundation for improving AF management outcomes.

Indexed as

Action PotentialsAtrial FibrillationCatheter AblationHeart AtriaHeart Conduction SystemHeart RateModels, CardiovascularAnimalsHumansNonlinear DynamicsTreatment Outcomeatrial electrophysiological propertiesatrial fibrillationcatheter ablationleft atrial remodelingnonlinear dynamicsturbulent‐like electrical activity

Identifiers

PMID41423702
PMCPMC12891294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.