Evidence map›Paper›PMID 41423593›Full record

ReviewAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2026

Zirconium-based metal-organic frameworks for pathogen detection.

Xiaoqing Cao, Yurou Kang, JingJing Li, Menqiu Xiong, Zhenlin Nie, Bangshun He

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Molecular sensing using metal-organic frameworks.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoqing CaoDepartment of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Yurou KangDepartment of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
JingJing LiDepartment of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Menqiu XiongDepartment of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Zhenlin NieDepartment of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China. zhenlinnie@126.com.
Bangshun HeDepartment of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China. bhe@njmu.edu.cn.

Funding

Jiangsu Provincial Medical Key Discipline Cultivation Unit JSDW202239Nanjing Medical Key Laboratory of laboratory diagnostics Nanjing Medical Key Laboratory of laboratory diagnosticsNational Natural Science Foundation of China 82472379project supported by Nanjing Medical Science and technology development Foundation ZKX23028
6 · The paper itself

Abstract

Pathogenic microorganisms pose severe threats to global public health, demanding rapid and accurate detection strategies. This review comprehensively summarizes recent advances in zirconium-based metal-organic frameworks (Zr-MOFs) for pathogen separation and biosensing. Leveraging high stability, large surface area, and ease of binding to biomolecules, Zr-MOFs-functionalized magnetic composites enable efficient enrichment via specific aptamer binding or label-free adsorption. In biosensing, they serve as versatile platforms: enhancing electrochemical sensitivity with conductive materials/enzymes; offering excellent fluorescence performance via quenching properties, tunable ligands or doped metals; and enabling rapid visual detection through colorimetric characteristics and peroxidase-like activity. Ratiometric signals further enhance reliability in complex matrices, and dual-signal systems expand their application scope. In addition, multimode signal output platforms based on Zr-MOFs are evolving to meet the needs of different situations. These technologies are fast, sensitive, economical, and continue to evolve toward point-of-care testing, offering promising solutions to the challenges of pathogen diagnosis.

Indexed as

BacteriaBiosensing TechniquesMetal-Organic FrameworksZirconiumHumansMetal-Organic FrameworksZirconiumBacteriaBiosensorMagnetic separationMetal–organic frameworkVirus

Identifiers

PMID41423593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.