ArticleJournal of microbiology and biotechnology2025
Isochlorogenic Acid C and
Article in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastritis is a common inflammatory gastrointestinal disease affecting approximately 40% of the global population. Alcohol abuse is a major contributor to gastritis, primarily acting through gastric mucosal injury and inflammation. Given the association between alcohol consumption and severe gastrointestinal complications, safe and effective strategies for the prevention and treatment of gastritis are urgently needed. This study investigated the pathophysiological effects of ethanol (EtOH) on gastric tissues using an EtOH-HCl-treated acute gastritis mouse model, EtOH-treated AGS gastric epithelial cells, and LPS-treated RAW 264.7 macrophages. We found that EtOH induces acute gastritis by damaging the gastric mucosa, elevating oxidative stress, and disrupting mitochondrial function. We identified Isochlorogenic acid C (ICAC) as a promising therapeutic candidate to counteract these detrimental effects. In the mouse model, oral administration of ICAC significantly alleviated acute gastritis by preserving mucosal integrity, preventing prostaglandin E
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.