Evidence map›Paper›PMID 41422873›Full record

ArticleAnnals of epidemiology2026

Multilevel modeling in egocentric network analysis: A practical guide with SAS and R.

Hongjie Liu

Abstract read
In one paragraph

Article in Annals of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

1 author.

Hongjie LiuDepartment of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park, United States. Electronic address: hliu1210@umd.edu.

Funding

Social network and sexual risk for HIV/STIs among older female sex workersR01HD068305 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI LIU, HONGJIE · 2011 to 2014
$1.6M
NICHD NIH HHS R01 HD068305
6 · The paper itself

Abstract

purposeThis paper illustrates the application of multilevel modeling to egocentric network data, where network alters are nested within their respective egos. The nested structure and intra-ego dependencies in such data violate the independence assumptions of traditional regression models.

methodsMultilevel modeling addresses this dependency by accommodating hierarchical data structures, allowing for more accurate estimation of ego-alter associations. It also distinguishes the effects of variables measured at the alter, ego, and dyadic (ego-alter) levels on outcome variable. We describe model specifications involving random intercepts and slopes, cross-level interactions, and assumptions related to residuals and variance structures. An illustrative example is provided to demonstrate how to estimate fixed and random effects for both continuous and binary outcome variables, assess intraclass correlation, test cross-level interactions, and interpret model results.

resultsThis paper serves as a practical guide for applying multilevel models to egocentric network data, outlining key conceptual foundations, methodological considerations, and step-by-step implementation using SAS and R.

conclusionsThe guide aims to support researchers in the social and health sciences in rigorously applying multilevel modeling to egocentric network data, fostering deeper insights into how individual, relational, and structural factors influence health-related outcomes.

Indexed as

EgoModels, StatisticalMultilevel AnalysisSocial SupportHumansApplicationDependenceEgocentric networkMultilevel analysisRandom effect

Identifiers

PMID41422873
PMCPMC13109971

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.