Evidence map›Paper›PMID 41422798›Full record

ArticleTalanta2026

Calibration-free ion-selective electrodes: A critical review of design strategies, materials, and applications in sensing.

Pavel Sengupta, Dipankar Koley

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Talanta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pavel SenguptaDepartment of Chemistry, Oregon State University, Corvallis, 97331, USA.
Dipankar KoleyDepartment of Chemistry, Oregon State University, Corvallis, 97331, USA. Electronic address: Dipankar.Koley@oregonstate.edu.

Funding

Microenvironmental characterization and manipulation to prevent secondary cariesR01DE027999 · NIDCR · OREGON STATE UNIVERSITY · PI Dipankar Koley · 2018 to 2026
$3.6M
Development of an Integrated Dental Plaque Bioanalytical Platform for Point-of-Care Diagnostics of Oral DiseasesR21DE034919 · NIDCR · OREGON STATE UNIVERSITY · PI KOLEY, DIPANKAR · 2025 to 2025
$423k
Going Local: Probing Real-Time Chemical Exchange Between Biofilm and Dental CompositesR21DE025370 · NIDCR · OREGON STATE UNIVERSITY · PI KOLEY, DIPANKAR · 2015 to 2016
$408k
NIDCR NIH HHS R01 DE027999NIDCR NIH HHS R21 DE025370NIDCR NIH HHS R21 DE034919
6 · The paper itself

Abstract

Ion-selective electrodes (ISEs) are powerful analytical tools for potentiometric ion sensing, yet their widespread application, particularly in decentralized and real-time monitoring, has been perennially constrained by the need for frequent and technically demanding calibration. This procedural bottleneck undermines their utility for portable, wearable, and in situ deployments. The development of calibration-free ISEs (CF-ISEs) represents a paradigm shift that aims to decouple the ion concentration measurements from the prerequisite of on-site calibration. In this review, we critically examine the foundational principles and core requirements that define this emerging class of sensors. We explore the diverse and innovative mechanisms enabling calibration-free operation, categorizing them as ion-to-electron transduction modes, structural and material innovations, and electrochemical conditioning techniques. A specific case study on screen-printed ISEs for Na

Indexed as

Calibration-freeElectrochemical sensorsIon-selective electrodePoint-of-care testingPotentiometrySolid contact

Identifiers

PMID41422798
PMCPMC12765629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.