Evidence map›Paper›PMID 41422714›Full record

ArticleJournal of inorganic biochemistry2026

Structure-activity relationships in catalytic amyloids.

Shams Aaghaz, Liam R Marshall, Ivan V Korendovych

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shams AaghazDepartment of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, TX 76706, United States of America.
Liam R MarshallDepartment of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, TX 76706, United States of America.
Ivan V KorendovychDepartment of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, TX 76706, United States of America. Electronic address: ivan_korendovych@baylor.edu.

Funding

TR&D 4 for ACERT, 2017-2021 funding periodP41GM103521 · NIGMS · CORNELL UNIVERSITY · PI FREED, JACK H · 2012 to 2021
$11.7M
Understanding Evolution of Protein Function Through Design.R35GM119634 · NIGMS · SYRACUSE UNIVERSITY · PI KORENDOVYCH, IVAN V · 2016 to 2025
$4.3M
NIGMS NIH HHS P41 GM103521NIGMS NIH HHS R35 GM119634
6 · The paper itself

Abstract

Short peptide-based assemblies combined with metal ions are simple yet effective platforms for catalysis. This study investigates the catalytic properties of de novo amyloid forming peptides, how their catalytic properties change with a range of hydrolysis substrates and the relationship between catalysis and structural characteristics. We have shown that even slight modifications in peptide sequence have a drastic impact on catalytic efficiency and substrate selectivity. We have also established k

Indexed as

AmyloidPeptidesCatalysisHydrolysisStructure-Activity RelationshipSubstrate SpecificityAmyloidPeptidesAmyloidCatalysisEnzyme designPeptidesSelf-assemblySubstrate preference

Identifiers

PMID41422714
PMCPMC13613369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.