Evidence map›Paper›PMID 41422124›Full record

ArticleScientific reports2025

The application of local lesion postoperative continuous irrigation for the perioperative management of spinal tuberculosis with posterior-only approach surgery.

Lige Xiao, Gengming Zhang, Manini Daudi Romani, Emmanu El Alonge, Jinyang Liu, Ang Deng

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Lige XiaoDepartment of Spine Surgery and Orthopaedics, Xiangya Hospital, Central-South University, Changsha, China.
Gengming ZhangDepartment of Spine Surgery and Orthopaedics, Xiangya Hospital, Central-South University, Changsha, China.
Manini Daudi RomaniDepartment of Spine Surgery and Orthopaedics, Xiangya Hospital, Central-South University, Changsha, China.
Emmanu El AlongeDepartment of Spine Surgery and Orthopaedics, Xiangya Hospital, Central-South University, Changsha, China.
Jinyang LiuDepartment of Spine Surgery and Orthopaedics, Xiangya Hospital, Central-South University, Changsha, China.
Ang DengDepartment of Spine Surgery and Orthopaedics, Xiangya Hospital, Central-South University, Changsha, China. deng.ang@csu.edu.cn.

Funding

the Degree & Postgraduate Education Reform Project of Central South University 2024JGB017the Degree & Postgraduate Education Reform Project of Hunan Province 2024JGYB020
6 · The paper itself

Abstract

To investigate the differences in perioperative indices, including experimental results and quality-of-life-related scores between patients managed with postoperative irrigation and drainage and those managed with drainage alone. This was a retrospective analysis of 88 patients with spinal tuberculosis who underwent surgical treatment at our spinal surgery center from January 2017 to January 2022, including 32 patients with continuous postoperative irrigation and 56 patients with postoperative drainage alone. Demographic and general characteristics, laboratory data, quality-of-life-related data, and complications were compared. Compared the drainage-only group, the inflammation-related index decreased more rapidly when local irrigation was performed. The ESR decreased from 65.7 ± 15.6 to 45.6 ± 8.3 in the irrigation group and from 64.2 ± 12.1 to 56.3 ± 6.5 in the drainage-only group during the first postoperative week. The VAS score also improved significantly in both the irrigation and drainage-only groups. In addition, the neurological condition improved to a greater extent at 2 weeks after surgery in the irrigation group, although a significant difference was not detected between the two groups. The average bed rest time of the irrigation group was longer than that of the drainage-only group, and the D-dimer level increased more in the irrigation group than in the drainage-only group at one week. Compared with the preoperative HADS score, the postoperative HADS score clearly decreased in both groups, and the irrigation group had better mental health conditions than the drainage-only group. Postoperative continuous irrigation combined with drainage is an optional perioperative management strategy that can significantly improve inflammatory and mental conditions compared with postoperative drainage alone, resulting in better clinical outcomes at the early postoperative stage.

Indexed as

Perioperative CareTherapeutic IrrigationTuberculosis, SpinalAdultAgedDrainageFemaleHumansMaleMiddle AgedPostoperative CarePostoperative ComplicationsQuality of LifeRetrospective StudiesTreatment OutcomeMental health conditionPostoperative irrigationPostoperative managementSpinal tuberculosis

Identifiers

PMID41422124
PMCPMC12834998

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.