Evidence map›Paper›PMID 41422024›Full record

SynthesisJournal of neuroengineering and rehabilitation2025

Technologies for the three-dimensional assessment and treatment of unilateral spatial neglect in individuals with stroke: a systematic review.

Daniele Somma, Alice Finocchi, Silvia Campagnini, Ester Marra, Chiara Pedrini, Samuele Pinna, Maria Anna Szczepanska, Alessio Fasano, Francesca Cecchi, Egidio Falotico and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniele SommaThe BioRobotics Institute, Scuola Superiore Sant'Anna, Pontedera, Italy.
Alice FinocchiIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.
Silvia CampagniniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.
Ester MarraIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy. emarra@dongnocchi.it.
Chiara PedriniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.
Samuele PinnaIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.
Maria Anna SzczepanskaIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.
Alessio FasanoIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.
Francesca CecchiIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.
Egidio FaloticoThe BioRobotics Institute, Scuola Superiore Sant'Anna, Pontedera, Italy.
Andrea ManniniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Via di Scandicci 269, Firenze, 50143, Italy.

Funding

Ministero della Salute RF-2021-12375472Ministero dell'Università e della Ricerca PNC0000007
6 · The paper itself

Abstract

Unilateral spatial neglect (USN) is a failure to respond or orient to stimuli in contralesional space, not explained by primary sensory or motor deficits. It affects up to two-thirds of right hemisphere stroke survivors and significantly impacts rehabilitation and functional outcomes. Recent advances in three-dimensional (3D) technologies, such as virtual reality (VR) and robotics, offer promising tools for assessment and treatment, providing realistic scenarios and precise clinical stimulation. This systematic review explores the current use of 3D technologies in USN, focusing on their features, level of development, and reported outcomes. A structured search of four databases using the PICO format identified 37 relevant studies out of 2891. The most frequently employed technologies were immersive and non-immersive VR, augmented and mixed reality, and robotics. However, these tools are still in early experimental phases. Among the studies, 15 addressed assessment, 17 focused on treatment, and 5 were technical in nature. Key challenges include methodological variability and the lack of standardized protocols. Due to the heterogeneity of technologies and outcomes, a meta-analysis was not feasible. Future studies should adopt rigorous designs to validate these approaches and support their integration into clinical practice.

Indexed as

Perceptual DisordersRoboticsStrokeStroke RehabilitationVirtual RealityHumans3D rehabilitationRoboticsStrokeSystematic reviewTechnologyUnilateral spatial neglectVirtual realityWearable electronic devices

Identifiers

PMID41422024
PMCPMC12831373

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.