SynthesisAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Principles for Rigorous Design and Application of Synthetic Microbial Communities.
Synthesis in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Principles for Rigorous Design and Application of Synthetic Microbial Communities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Pooled it
- Harnessing synthetic microbial communities for desert vegetation restoration.Synthetic and systems biotechnology · 2027Review
- Synthetic microbial communities: emerging live biotherapeutics for targeted gut microbiome modulation.Gut microbes · 2026Review
- Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond-Specific Microbial Responders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Intelligent Plasmonic Bio-Holoelectrochemical Systems: A Testable Architecture for Light-Programmed Microbial Electrochemistry.Global challenges (Hoboken, NJ) · 2026Review
- SynComs should be rigorously defined, not renamed.Nature communications · 2026Article
- Polysaccharides PFP1-1 Activate Root "Recruitment Signals": Beneficial Bacteria-Mediated Rhizoctonia Resistance in Cotton.Plant, cell & environment · 2026Article
- Review
- Engineering Plant-Associated Soil Microbiomes for Sustainable and Climate-Resilient Agriculture: Mechanisms, Technologies, and Applications.Microorganisms · 2026Review
- Diversity of Soil Fungi, Entomopathogenic Fungi and Their Driving Factors in the Eastern Tanggula Mountains in the Qinghai-Tibet Plateau.Microorganisms · 2026Article
- Synthetic Microbial Community Biosensors: From Engineered Ecosystems to Modular Detection Platforms with AI-Driven Intelligence.Biosensors · 2026Review
- Elevational Variation in Rhizosphere Bacterial Assembly and Fine-Scale Taxon Differentiation ofMicroorganisms · 2026Article
- The Formation Mechanism and Regulation of Fermented Bean Paste Flavor: Microbial Community Succession, Flavor Compound Synthesis, and Applications of Intelligent Biomanufacturing Technology.Comprehensive reviews in food science and food safety · 2026Review
- Strain-Specific Fungal-Bacterial Co-Inoculation Regulates Rhizosphere Microecology and Plant-Soil-Microbiome Responses in Conifer Seedlings.Microorganisms · 2026Article
- Biocontrol Microbial Inoculants SuppressPlants (Basel, Switzerland) · 2026Article
- Omics-Guided Construction of Microbial Consortia for Reproducible Traditional Fermented Foods and Beverages.Foods (Basel, Switzerland) · 2026Review
- Synthetic Microbial Communities Enhance Artificial Cyanobacterial Crusts Formation via Spatiotemporal Synergy.Microorganisms · 2026Article
- Synthetic microbial communities: a novel emerging models for dissecting gut microbiota-host interactions in neurodegenerative diseases.Frontiers in immunology · 2026Review
- Decoding the rhizosphere microbiome againstFrontiers in microbiomes · 2026Review
- Microbial inoculants for soil restoration: a risk-proportional stewardship framework integrating strain-resolved genomics and adaptive governance.Sustainable microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Funding
Abstract
Synthetic microbial communities (SynComs) are microbial consortia with defined taxonomic and functional traits, so that the combination elicits a predictable response under defined conditions. SynComs are artificially designed to enable inter-species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. As an applied tool, SynComs have been deployed in diverse contexts, including agriculture, industry, and environmental ecology. This systematic review explores the processes used to construct SynComs, the mechanisms of metabolic interaction between members, and a review of the different ways that SynComs have been applied. We also explore the challenges for SynCom development and application, and future research directions that could overcome these challenges. SynComs are a powerful tool in our arsenal of applied technologies, but research and application are still nascent. While advances have been made, more research is needed to ensure SynCom technologies do not threaten global ecological security. SynCom technology represents a versatile platform for the controlled manipulation of microbial systems, enabling targeted modification of ecological and physiological processes. This emerging field marks a transition from descriptive biology toward a predictive and engineering-driven framework for understanding and shaping living systems.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.