Evidence map›Paper›PMID 41420829›Full record

SynthesisJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2026

Rehabilitation in Cases of Maxillary Lateral Incisor Agenesis Using Zirconia Implant and Abutment: Finite Element Analysis and Systematic Review.

Leonardo Folmer Rodrigues da Silva, Ivan Onone Gialain, Marina Guimarães Roscoe, Omar Melendres Ugarte, Paolo Maria Cattaneo, Josete Barbosa Cruz Meira

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leonardo Folmer Rodrigues da SilvaDepartment of Biomaterials and Oral Biology, School of Dentistry of University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-2837-2856
Ivan Onone GialainResearch Program on Integrated Dental Sciences, Faculty of Dentistry of the University of Cuiabá, Cuiabá, Brazil.ORCID https://orcid.org/0000-0002-0539-530X
Marina Guimarães RoscoeFaculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK.ORCID https://orcid.org/0000-0002-1670-4649
Omar Melendres UgarteDepartment of Biomaterials and Oral Biology, School of Dentistry of University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-8639-3025
Paolo Maria CattaneoFaculty of Medicine, Dentistry and Health Sciences, Melbourne Dental School, The University of Melbourne, Parkville, Australia.ORCID https://orcid.org/0000-0001-7604-3259
Josete Barbosa Cruz MeiraDepartment of Biomaterials and Oral Biology, School of Dentistry of University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-9589-2130

Funding

Coordenacao de Aperfeicoamento de Pessoal de Nivel SuperiorFundação de Amparo à Pesquisa do Estado de São Paulo 2023/07312-0
6 · The paper itself

Abstract

objectiveThe use of narrow-diameter implants has emerged as a strategy to compensate for the reduced bone dimensions of maxillary lateral incisor agenesis (MLIA). This study integrates finite element analysis (FEA) and systematic review (SR) to assess the biomechanical and clinical viability of implant-supported crowns in MLIA scenarios. MATERIALS AND

methodsThree-dimensional FEA were built, comprising a control and an atrophic model representative of an MLIA case. Simulations were performed using implants with varying diameters and materials. The risk of implant and abutment mechanical failure and bone resorption were evaluated. The SR was designed to evaluate the consistency between in silico predictions and clinical outcomes.

resultsReduced implant diameter was associated with an increased risk of implant fracture and bone resorption. All implants and abutments in the simulated models exhibited stress values below the critical threshold for titanium and zirconia failure, indicating a low mechanical failure risk under simulated conditions. Additionally, among the 25 studies included in the SR, 19 reported successful outcomes for implant therapy, but no zirconia implants were identified.

conclusionsTitanium implants with regular diameter combined with hybrid abutments demonstrated favorable biomechanical behavior and seem a reliable option for MLIA rehabilitation, offering both structural integrity and esthetic benefits. CLINICAL SIGNIFICANCE: The implant-prosthetic rehabilitation of MLIA has demonstrated high reliability and predictability in both esthetic and functional outcomes, especially when performed through a multidisciplinary approach involving orthodontics, periodontics, implantology, and prosthodontists. Long-term studies are still necessary to validate the longevity and performance of zirconia implants in MLIA.

Indexed as

AnodontiaDental AbutmentsDental ImplantsDental Prosthesis, Implant-SupportedIncisorZirconiumCrownsDental Restoration FailureFinite Element AnalysisHumansMaxillaDental ImplantsZirconiumzirconium oxideanterior maxillabiomechanical evaluationfinite element analysismaxillary lateral incisor agenesiszirconia implant

Identifiers

PMID41420829
PMCPMC13069213

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.