Evidence map›Paper›PMID 41420776›Full record

ArticleArchives of virology2025

Molecular characteristics of a novel alternavirus from Trichoderma harzianum.

Jeesun Chun, Yo-Han Ko, Dae-Hyuk Kim

Abstract read
In one paragraph

Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeesun Chun *Institute for Molecular Biology and Genetics, Jeonbuk National University, 567 Baekje-daero, 54896, Jeonju, Jeonbuk, Korea.
Yo-Han Ko *Institute for Molecular Biology and Genetics, Jeonbuk National University, 567 Baekje-daero, 54896, Jeonju, Jeonbuk, Korea.
Dae-Hyuk KimInstitute for Molecular Biology and Genetics, Jeonbuk National University, 567 Baekje-daero, 54896, Jeonju, Jeonbuk, Korea. dhkim@jbnu.ac.kr.ORCID http://orcid.org/0000-0002-9948-5313

Funding

National Research Foundation of Korea National Research Foundation of Korea
6 · The paper itself

Abstract

We analyzed the dsRNA profiles of Trichoderma spp. and identified a novel mycovirus from Trichoderma harzianum strain NFCF419. Phylogenetic and genomic analysis suggested that this virus is a novel member of the family Alternaviridae. Next-generation sequencing (NGS) analysis revealed that this virus consisted of four genome segments. The complete genome sequences of the segments were determined by NGS, and the NGS results were confirmed by manual sequencing of RT-PCR amplicons using specific primer pairs. 5’- and 3’-RACE was performed to determine the terminal sequences of each segment. The genome segments were found to be 3,572 bp (dsRNA1), 2,552 bp (dsRNA2), 2,593 bp (dsRNA3), and 1,484 bp (dsRNA4) in size. The largest segment (dsRNA1) contains a single open reading frame (ORF) encoding a putative RNA-dependent RNA polymerase (RdRP). dsRNA2, 3, and 4 each contain a single ORF encoding a putative methyltransferase, a coat protein, and a hypothetical protein with unknown function, respectively. Evaluation of the genome organization, analysis of the deduced amino acid sequence of the RdRP, and phylogenetic analysis indicated that this virus is a new member of the genus Alternavirus in the family Alternaviridae. Accordingly, we designated this novel mycovirus "Trichoderma harzianum alternavirus 1" (ThAV1). This is the first report of a mycovirus of the family Alternaviridae that infects a member of the genus Trichoderma.

Indexed as

Fungal VirusesHypocrealesRNA VirusesAmino Acid SequenceGenome, ViralHigh-Throughput Nucleotide SequencingOpen Reading FramesPhylogenyRNA-Dependent RNA PolymeraseRNA, Double-StrandedRNA, ViralViral ProteinsRNA-Dependent RNA PolymeraseRNA, Double-StrandedRNA, ViralViral ProteinsAlternavirusMycovirusTrichoderma

Identifiers

PMID41420776
PMCPMC12718280

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.