ArticleAnalytical and bioanalytical chemistry2026
Advancing spatial-omics through Pyxis, vendor-neutral software for ion mobility mass spectrometry imaging data analysis.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- TIMSImaging: an open and interoperable workflow for trapped ion mobility mass spectrometry imaging data processing and visualization.Bioinformatics (Oxford, England) · 2026Article
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6 authors.
Funding
Abstract
Mass spectrometry imaging (MSI) is a powerful analytical technique suited for simultaneously measuring and assigning functional roles of multiple analytes directly from intact tissue sections. MSI acquisitions often lead to highly complex datasets with numerous isobaric species. Ion mobility (IM) spectrometry crucially helps to unravel these datasets by providing an orthogonal separation thus supplementing the lack of chromatographic separation in MSI. However, the rich, multidimensional data produced by IM-MSI investigations, combined with the lack of comprehensive software solutions that support the entire data analysis workflow, poses a major challenge preventing IM-MSI full exploitation. Here, we discuss the benefits and challenges of IM-MSI data analysis in metabolomic applications. Finally, Pyxis, a novel, vendor-neutral IT solution for IM-MSI data analysis, is introduced and its capabilities demonstrated on mouse kidney tissue and THP-1 monocytes data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.