Evidence map›Paper›PMID 41420737›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Mirtazapine is a functional antagonist at cardiac human H

Thanh Hoai Pham, Jonas M A Schlicht, Britt Hofmann, Uwe Kirchhefer, Joachim Neumann, Ulrich Gergs

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Prokinetic drugs that stimulate 5-HTNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  2. On indirect negative inotropic effects of muscarine in the isolated human atrium.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  3. Anxiolytic-Like Effect ofACS omega · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thanh Hoai PhamInstitute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany.
Jonas M A SchlichtInstitute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany.
Britt HofmannDepartment of Cardiac Surgery, Mid-German Heart Centre, University Hospital Halle, Ernst-Grube-Straße 40, 06097, Halle (Saale), Germany.
Uwe KirchheferInstitute for Pharmacology and Toxicology, University Hospital Münster, University Münster, Domagkstraße 12, 48149, Münster, Germany.
Joachim NeumannInstitute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany. joachim.neumann@medizin.uni-halle.de.
Ulrich GergsInstitute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany.

Funding

Deutsche Forschungsgemeinschaft 528629916
6 · The paper itself

Abstract

Mirtazapine is an atypical tetracyclic antidepressant drug that binds to several monoamine neurotransmitter receptors. For instance, mirtazapine binds to H

Indexed as

Histamine H1 AntagonistsMianserinMirtazapineReceptors, Histamine H1AdultAnimalsDose-Response Relationship, DrugFemaleHeart AtriaHumansMaleMiceMice, TransgenicMiddle AgedMyocardial ContractionMyocytes, CardiacHistamine H1 AntagonistsMianserinMirtazapineReceptors, Histamine H1ChronotropyH1-histamine receptorHeartInotropyMirtazapine

Identifiers

PMID41420737
PMCPMC13086767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.