Evidence map›Paper›PMID 41420656›Full record

ArticleActa neurochirurgica2025

Impact of removal of the lateral orbital rim on intraorbital pressure during endoscopic trans-orbital approach (ETOA): a cadaveric study.

Antonio Strangio, Joel Davaine Ndongo Sonfack, Marc-Olivier Comeau, Guilherme Gago, Annie Moreau, Martìn Coté, Pierre-Olivier Champagne

Abstract read
In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Antonio StrangioDepartment of Neurosurgery, CHU de Québec - Université Laval, Québec, Canada. to.strangio@gmail.com.
Joel Davaine Ndongo SonfackFaculté de Médicine, CHU de Québec - Université Laval, Québec, Canada.
Marc-Olivier ComeauFaculté de Médicine, CHU de Québec - Université Laval, Québec, Canada.
Guilherme GagoDepartment of Neurosurgery, CHU de Québec - Université Laval, Québec, Canada.
Annie MoreauDepartment of Ophtalmology, CHU de Québec - Université Laval, Québec, Canada.
Martìn CotéDepartment of Neurosurgery, CHU de Québec - Université Laval, Québec, Canada.
Pierre-Olivier ChampagneDepartment of Neurosurgery, CHU de Québec - Université Laval, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe endoscopic transorbital approach (ETOA) is being established as a new corridor for the lateral portion of the anterior and middle skull base. One of the main concerns is the risk of ophthalmological complications due to orbital retraction. Removal of the lateral orbital rim (LOR) is a simple measure that widens the corridor and may diminish injuries secondary to retraction. This study analyzes the impact of LOR removal on intraorbital pressure (IORP) during the stages of ETOA.

methodsIn this prospective cadaveric study, standard ETOA to the anterior and middle fossae were performed via a superior eyelid crease incision (Fig. 2). On one side, the LOR was preserved; on the other, it was removed. IORP was recorded with an intracranial pressure (ICP) probe during the entirety procedure (Fig. 3). All specimens underwent pre- and post-procedure CT to measure bone removal volume.

resultsFour specimens were used (8 sides, 4 with LOR removal, 4 without). Mean IORP was not statistically different between groups during periorbita detachment, which was prior to LOR removal (117.4 vs 91.5 mmHg, for the LOR removal group and LOR intact group respectively p = 0.217). IORP was consistently reduced in the LOR removal group in every subsequent step (Fig. 3): meningo-orbital band cutting (105.5 to 38.9 mmHg, p < 0.002), temporal fossa drilling (85.3 to 69.5 mmHg, p = 0.232), lateral greater sphenoid wing (GSW) drilling (99.8 to 49.9 mmHg, p < 0.001), medial GSW drilling (85.6 to 17.2 mmHg, p < 0.001), cavernous sinus peeling (85.6 to 3.0 mmHg, p < 0.001). LOR removal increased total bone removal volume from 6.2 cc to 9.4 cc (p = 0.05).

conclusionLOR removal decreased IORP, especially when working on the GSW and cavernous sinus, and significantly increased bone removal. These results support LOR removal to reduce orbital retraction stress and widen the working corridor during ETOA.

Indexed as

EndoscopyIntracranial PressureNeuroendoscopyOrbitCadaverHumansProspective StudiesEndoscopicEye pressureLateral orbital rimOrbitotomySkull baseTransorbital

Identifiers

PMID41420656
PMCPMC12722340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.