Trial report in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors.
Jacob E MatneyHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0009-0003-1969-4639
Alexander A BuelowHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0003-0743-391X
Chris MixonHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0009-0005-4065-0301
Sarah M SkillettHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0009-0001-5163-8253
John D AshleyHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0003-0836-424X
Jiwon SongHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.
Amir Akbari FakhrabadiHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0002-0686-8121
Paige PointerHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.
Justin D SprickDepartment of Kinesiology, Health Promotion, and Recreation, University of North Texas, Denton, Texas, USA.ORCID 0000-0001-9782-1865
Christopher D BlackSensory and Muscle Function Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.
Hugo M PereiraHuman Movement and Neurophysiology Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0003-4373-7005
J Mikhail KellawanHuman Circulation Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0001-7889-8146
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Cerebrovascular CYP450 is underexplored in humans. Twenty-three participants (12 females) completed familiarization and two experimental visits utilizing double-blind, randomized, crossover design. Participants ingested fluconazole (150 mg; FLZ, CYP450 inhibitor) or placebo (PLC, microcrystalline cellulose) followed by 120 min of supine rest. Five minutes of middle cerebral artery velocity (MCAv) and mean arterial pressure (MAP) were collected during rest (PLC/FLZ
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
The effects of CYP450 inhibition on cerebrovascular control during rest and mild hypovolemia: An exploratory study in young, healthy adults. · full record | OpenQuestion