Evidence map›Paper›PMID 41420384›Full record

SynthesisPhysiological reports2025

Acute effects of resistance exercise on skeletal muscle glycogen depletion: A systematic review and meta-analysis.

Amin Hamidvand, Slaheddine Delleli, Jeffrey A Rothschild, Farzaneh Chenaghchi, Afshar Jafari, Alireza Naderi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amin HamidvandDepartment of Biological Sciences in Sport, Faculty of Sport Sciences and Health, Shahid Beheshti University, Tehran, Iran.ORCID 0000-0002-4705-8918
Slaheddine DelleliHigh Institute of Sport and Physical Education, University of Sfax, Sfax, Tunisia.ORCID 0000-0003-0013-8774
Jeffrey A RothschildSports Performance Research Institute New Zealand, Auckland University of Technology, Auckland, New Zealand.ORCID 0000-0003-0014-5878
Farzaneh ChenaghchiDepartment of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht, Iran.ORCID 0009-0006-8767-1166
Afshar JafariDepartment of Biological Sciences in Sport, Faculty of Sport Sciences and Health, Shahid Beheshti University, Tehran, Iran.
Alireza NaderiDepartment of Sport Physiology, Faculty of Human Sciences, Borujerd Branch, Islamic Azad University, Borujerd, Iran.ORCID 0000-0002-8539-4306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compile and statistically summarize quantitative evidence on the acute effects of resistance training sessions on muscle glycogen concentration, a systematic search was conducted on Pubmed, Web of Science, and Scopus databases up to 28th July 2024. Twenty studies including 168 male and 12 female participants were eligible. A multilevel, random-effects meta-analysis was used to calculate the overall mean difference (MD) with a 95% confidence interval (CI) and prediction interval (PI). The model (28 effect sizes across 20 clusters) revealed a significant glycogen decrease (MD = -104.3; 95% CI: -137.6 to -71.0; PI: -244.4 to 35.7; p < 0.001). Meta-regression showed greater depletion with more sets (Estimate = -11.2; 95% CI: -18.0 to -4.3; p = 0.001) and longer session duration (Estimate = -1.3; 95% CI: -2.3 to -0.3; p = 0.009), but less with higher intensity (Estimate = 2.88; 95% CI: 1.2 to 4.5; p = 0.0006). Subgroup analysis showed greater depletion with varied intensity (MD = -162.9) versus fixed (MD = -82.5), and in untrained (MD = -113.0) versus trained participants (MD = -101.3). A single resistance training session depletes glycogen in the vastus lateralis muscle, with depletion influenced by training intensity, session duration, number of sets within session and training status.

Indexed as

GlycogenMuscle, SkeletalResistance TrainingFemaleHumansMaleGlycogenCarbohydrateenergyexercisemetabolismperformance

Identifiers

PMID41420384
PMCPMC12717450

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.