Evidence map›Paper›PMID 41420352›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2026

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation.

Xiaohui Ju, Roshan Velluvakandy, Xianghua Wu, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Kamila Bendíčková, Jan Frič, Martin Pumera

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaohui JuFuture Energy and Innovation Laboratory, Central European Institute of Technology, Brno University of Technology, Purkyňova 123, Brno, 61200, Czech Republic.ORCID https://orcid.org/0000-0002-4468-6003
Roshan VelluvakandyFuture Energy and Innovation Laboratory, Central European Institute of Technology, Brno University of Technology, Purkyňova 123, Brno, 61200, Czech Republic.ORCID https://orcid.org/0009-0006-4356-2363
Xianghua WuFuture Energy and Innovation Laboratory, Central European Institute of Technology, Brno University of Technology, Purkyňova 123, Brno, 61200, Czech Republic.ORCID https://orcid.org/0009-0006-9308-1883
Miguel Angel Merlos RodrigoDepartment of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1665/1, Brno, 61300, Czech Republic.ORCID https://orcid.org/0000-0002-1920-0948
Zbyněk HegerDepartment of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1665/1, Brno, 61300, Czech Republic.ORCID https://orcid.org/0000-0002-3915-7270
Kamila BendíčkováInternational Clinical Research Center, St. Anne's University Hospital, Pekařská 664/53, Brno, 60200, Czech Republic.ORCID https://orcid.org/0000-0001-7767-1003
Jan FričInternational Clinical Research Center, St. Anne's University Hospital, Pekařská 664/53, Brno, 60200, Czech Republic.ORCID https://orcid.org/0000-0001-6642-797X
Martin PumeraFuture Energy and Innovation Laboratory, Central European Institute of Technology, Brno University of Technology, Purkyňova 123, Brno, 61200, Czech Republic.ORCID https://orcid.org/0000-0001-5846-2951

Funding

China Scholarship Council 202306950103ERDF/ESF No.CZ.02.01.01/00/22_008/0004587European Union Jan Amos Komensky Operational Program No.CZ.0.2.0.1.0.1/00/22_008/000463Grant Agency of the Czech Republic 25-15484XGrant Agency of the Czech Republic EXPROMEYS CR LM2023051Ministry of Health of the Czech Republic No.NW24-08-00276
6 · The paper itself

Abstract

Soft microrobots, compared with their rigid counterparts, offer superior adaptability in dynamic and confined biological environments. Here, magnetically-guided liquid metal microrobots composed of gallium-indium alloys embedded with Fe nanoparticles are introduced. The unique combination of magnetic maneuverability, high surface tension, intrinsic radiopacity, and deformability allows liquid metal-based microbots to overcome limitations of both hard microrobots and fragile droplet-based systems. Under magnetic actuation, liquid metal-based magnetic microrobots exhibit controllable rolling and upstream locomotion resembling neutrophil-like navigation, enabling precise maneuvering even against physiological flow. Bridging in vitro with in vivo experiments, quail egg chorioallantoic membrane models are used to demonstrate guided transport of these microrobots through blood vessels, accumulation at tumor xenografts, and migration within subcutaneous tissues. Moreover, their strong X-ray visibility enables real-time fluoroscopic tracking, validated in porcine heart vasculature. Importantly, liquid metal-based magnetic microbots can cross endothelial barriers in a vascular flow-on-a-chip platform, while maintaining endothelial biocompatibility. By integrating deformability, magnetic steerability, and imaging visibility, liquid metal-based microrobots establish a powerful platform for minimally invasive transvascular navigation. This work highlights the potential of liquid metal-based magnetic microrobots for targeted drug delivery, image-guided therapy, and intelligent biomedical interventions.

Indexed as

RoboticsAlloysAnimalsChorioallantoic MembraneGalliumHumansIronSwineAlloysGalliumIroncross‐membranegallium‐indiumliquid metalorgan‐on‐a‐chipradiopaquereconfigurabletargeted delivery

Identifiers

PMID41420352
PMCPMC13054206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.