Evidence map›Paper›PMID 41420238›Full record

ArticleMalaria journal2025

Comparative larvicidal efficacy of essential oils from Cymbopogon citratus stalks and leaves against Anopheles gambiae sensu stricto.

Eugene Mutagwaba, Raymond Urassa, Eliot Ngenda, Tanga Mafuru, Raphael Matinde, Emmanuel Kimaro, James Kapala, Adelina Thomas, Tekla Joseph, Amos Luanda

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eugene Mutagwaba *Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.
Raymond Urassa *Department of Chemistry, College of Natural and Mathematical Sciences, University of Dodoma, P.O. Box 338, Dodoma, Tanzania.
Eliot Ngenda *Department of Chemical Engineering, School of Chemistry and Chemical Engineering, Huaiyin Institute of Technology, Huai'an, 223003, Jiangsu, China.
Tanga MafuruDepartment of Medicinal Chemistry and Pharmacognosy, School of Pharmacy, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania. tangabonny@gmail.com.
Raphael MatindeDepartment of Medicinal Chemistry and Pharmacognosy, School of Pharmacy, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.
Emmanuel KimaroDepartment of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.
James KapalaDepartment of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.
Adelina ThomasDepartment of Medicinal Chemistry and Pharmacognosy, School of Pharmacy, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.
Tekla JosephDepartment of Medicinal Chemistry and Pharmacognosy, School of Pharmacy, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.
Amos LuandaDepartment of Chemistry, College of Natural and Mathematical Sciences, University of Dodoma, P.O. Box 338, Dodoma, Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMosquitoes transmit several infectious diseases, including malaria. Due to the increasing resistance of mosquitoes to synthetic insecticides and the non-selective nature of these chemicals, larviciding has emerged as an effective and environmentally safer method of mosquito control. This study focused on the larvicidal activity of the essential oils (EOs) isolated from Cymbopogon citratus (lemongrass) stalks and leaves collected in Morogoro, Tanzania, against Anopheles gambiae sensu stricto (s.s.) larvae.

methodsThe EOs were extracted by hydrodistillation and characterized by Gas Chromatography-Mass Spectroscopy (GC-MS). Larvicidal bioassays were performed on laboratory-reared larvae, and mortality data were analysed using probit analysis to determine LC

resultsA total of 195 and 99 components from the lemongrass leaves and stalks, respectively, were identified. The higher concentration of EOs was obtained from stalks in comparison to the leaf's counterpart, in which the geranial (31.89%) and neral (27.02%) were determined to be the major components. The EOs isolated from lemongrass stalks demonstrated greater larvicidal activity than those obtained from lemongrass leaves, with LC

conclusionThe EOs from lemongrass stalks exhibit greater larvicidal efficacy against An. gambiae s.s. larvae compared to those obtained from lemongrass leaves.

Indexed as

AnophelesCymbopogonInsecticidesOils, VolatileAnimalsGas Chromatography-Mass SpectrometryLarvaMosquito ControlMosquito VectorsPlant LeavesTanzaniaInsecticidesOils, VolatileAnopheles gambiae s. s. larvae.Cymbopogon citratusEssential oilsLarvicidal activity

Identifiers

PMID41420238
PMCPMC12717681

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.