Evidence map›Paper›PMID 41420144›Full record

ArticleBMC microbiology2025

Genomic and phenotypic diversities among Bacillus cereus isolates from cosmetics.

Nadine Yossa, Roma Adu-Osei, Travis Canida, Gopal Gopinath, Rachel Binet

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Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nadine YossaFood and Drug Administration/Human Foods Program/Office of Laboratory Operations and Applied Science, Office of Applied Microbiology and Technology, College Park, MD, 20740, USA. IreneNadine.Tchagou@fda.hhs.gov.
Roma Adu-OseiOak Ridge Institute for Science and Education, Oak Ridge, TN, 37831, USA.
Travis CanidaFDA/HFP/Office of Surveillance Strategy and Risk Prioritization, Division of Surveillance and Data Integration/Surveillance Design Branch, College Park, MD, 20740, USA.
Gopal GopinathFood and Drug Administration/Human Foods Program/Office of Laboratory Operations and Applied Science, Office of Applied Microbiology and Technology, College Park, MD, 20740, USA.
Rachel BinetFood and Drug Administration/Human Foods Program/Office of Laboratory Operations and Applied Science, Office of Applied Microbiology and Technology, College Park, MD, 20740, USA.

Funding

Not Applicable NA
6 · The paper itself

Abstract

backgroundAs Bacillus cereus species can negatively affect the safety and quality of both food and non-food products, it would be useful to describe among the selected strains traits supporting survival in specific matrices. We recently characterized the genome of 3 A ES, a B. cereus isolated from eye shadow, revealing multiple genes predicted to support the adaptation of this strain to harsh environmental conditions. Here, we compared the genotypic and phenotypic relative sensitivity/ resistance of B. cereus 3 A ES with two additional B. cereus cosmetic isolates: an eye shadow isolate, 7 C ES, a baby wipe isolate, 1 L BW, as well as clinical strain American Type Culture Collection (ATCC) 49,063, an emetic strain from unknown origin F60006, the ATCC 14,579 reference type strain, and a non-cereus strain, B. pumilus ATCC 7061. An additional eye shadow isolate, 8 A ES, was only tested phenotypically.

resultsBTyper, the B. cereus subtyping tool within the FDA HFP GalaxyTrakr bioinformatic platform, separated the strains in three phylogenetic groups, with B. pumilus as an outlier. Four strains were identified as B. cereus sensu stricto (s.s.), group IV: 3 A ES, ATCC strains 14,579 and 49,063, with 7 C ES additionally identified as B. cereus s.s. biovar Thuringiensis. F60006 was recognized as B. mosaicus subsp. cereus Emeticus s.s., in group III. Isolate 1 L BW was identified as B. cytotoxicus, group VII. Analyses of these genomic sequences using the Pathosystems Resource Integration Center (BV-BRC - PATRIC) revealed genes predicting resistance for diverse antibiotic groups and biocides. B. cereus strains displayed resistance to most of the compounds tested with Vitek

conclusionAlthough these B. cereus strains exhibited a range of genotypic and phenotypic profiles, there were no traits distinguishing isolates from cosmetics from the isolates from non-cosmetics tested. Further, antimicrobial resistance was not only dependent on the arsenal carried by a given strain but also on the concentration of each antibiotic.

Indexed as

Bacillus cereusCosmeticsGenetic VariationGenome, BacterialAnti-Bacterial AgentsGenomicsGenotypeHumansMicrobial Sensitivity TestsPhenotypePhylogenyAnti-Bacterial AgentsCosmeticsB. cereus Cosmetic IsolatesBV-BRCGalaxyTrakrGenotypicPhenotype Microarrays™PhenotypicResistanceSensitivityVITEK®2

Identifiers

PMID41420144
PMCPMC12831255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.