Evidence map›Paper›PMID 41420056›Full record

ArticleScientific reports2025

Thermally assisted microbot transport through high-viscosity media.

A K Ishiki, K B Neeves, D W M Marr

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A K IshikiDepartment of Chemical and Biological Engineering, Colorado School of Mines, Golden, CO, USA.
K B NeevesDepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
D W M MarrDepartment of Chemical and Biological Engineering, Colorado School of Mines, Golden, CO, USA. dmarr@mines.edu.

Funding

Magnetically propelled microwheels for rapid thrombolysis in small arteriesR01NS102465 · NINDS · COLORADO SCHOOL OF MINES · PI MARR, DAVID WM, NEEVES, KEITH B · 2018 to 2022
$2.6M
Airborne delivery of microbots for chemical and mechanical attack of pulmonary biofilmsR21AI138214 · NIAID · COLORADO SCHOOL OF MINES · PI MARR, DAVID WM, NEEVES, KEITH B · 2019 to 2020
$419k
Colorado Office of Economic Development and International Trade #CTGG12025-2438NIAID NIH HHS R21 AI138214NIH HHS R01NS102465NINDS NIH HHS R01 NS102465
6 · The paper itself

Abstract

Many potential in vivo microbot (µbot) applications require transport through high-viscosity environments. We have previously demonstrated that rotating magnetic fields can be used to reversibly assemble and drive µbots composed of paramagnetic microparticles. In this, particle surface chemistry can be readily manipulated and the combination of chemical degradation and mechanical action used to enhance penetration of µbot swarms into gelled networks. Here we show that a thermal approach, created through a hyperthermia-induced heating of microparticles with complementary alternating magnetic fields, can also be used to enhance mechanical action by lowering local viscosity. In addition, we observe that a rapid µbot back and forth sweeping motion induced by the applied field significantly improves penetration rates by reducing both µbot size and viscous resistance.

Identifiers

PMID41420056
PMCPMC12830990

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.