ArticleAnalytical and bioanalytical chemistry2026
The benefits of multi-
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the demand in alternative medicine to treat various diseases, medicinal plants as ancient remedies gained more recent interest for the discovery and isolation of active compounds (Int J Environ Res Public Health. 2020;17(10):3376, J Ethnopharmacol. 2017;199:161-167). As these plant matrices contain an enormous range of metabolites, the challenge lies in the selection and application of separation techniques capable of resolving such complexity. For this reason, comprehensive two-dimensional liquid chromatography (LC × LC), due to the increased peak capacity compared to one-dimensional LC, was firstly selected for the chemical characterization of five European medicinal plants (Angelica archangelica, Angelica sylvestris, Agrimonia eupatoria, Sambucus ebulus, and Sambucus nigra). For the method development, complimentary columns were chosen, optimized, and compared regarding peak capacity, orthogonality, and peak distribution. Moreover, a platform with even higher separation power was chosen using a PFP column in the first dimension and two complimentary columns in the second dimension, ZIC-HILIC from 0 to 20 min and polar C18 from 20 min until 60 min at the end, called multi-
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.