Evidence map›Paper›PMID 41419652›Full record

ArticleCommunications biology2025

DNA repair pathway-related proteins are involved in the circularization step of microDNA eccDNA

Xinyu Tong, Qunnan Qiu, Xiaolong Hu, Zhe Liu, Mei Yin, Liuyang Li, Chao Lei, Yongjie Feng, Min Zhu, Chengliang Gong

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinyu Tong *School of Life Sciences, Soochow University, Suzhou, China.
Qunnan Qiu *School of Life Sciences, Soochow University, Suzhou, China.
Xiaolong Hu *School of Life Sciences, Soochow University, Suzhou, China.
Zhe LiuSchool of Life Sciences, Soochow University, Suzhou, China.
Mei YinSchool of Life Sciences, Soochow University, Suzhou, China.
Liuyang LiSchool of Life Sciences, Soochow University, Suzhou, China.
Chao LeiSchool of Life Sciences, Soochow University, Suzhou, China.ORCID http://orcid.org/0009-0004-0575-671X
Yongjie FengSchool of Life Sciences, Soochow University, Suzhou, China.
Min ZhuSchool of Life Sciences, Soochow University, Suzhou, China. zhumin990@suda.edu.cn.ORCID http://orcid.org/0009-0002-8929-115X
Chengliang GongSchool of Life Sciences, Soochow University, Suzhou, China. gongcl@suda.edu.cn.ORCID http://orcid.org/0000-0001-6545-727X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32372946, 32573297, 32072792 and 32202744
6 · The paper itself

Abstract

A large number of extrachromosomal circular DNAs (eccDNAs) are found in eukaryotic cells, but the mechanism behind the formation of eccDNAs remains unknown. EccDNAs smaller than 1000 bp are commonly referred to as microDNAs. In a prior study, we identified a 542 bp microDNA, designated eccDNA

Indexed as

BombyxDNA, CircularDNA RepairInsect ProteinsAnimalsDNA, CircularInsect Proteins

Identifiers

PMID41419652
PMCPMC12847890

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.