ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Validation of the Oncofertility Support Scale derived from the Fertility Information Support scale among young adult women with breast cancer.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Reproductive concerns and fertility intention among reproductive-age Chinese women with breast cancer: A multiple mediation analysis.Asia-Pacific journal of oncology nursing · 2026Article
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Abstract
purposeOncofertility support plays a critical role in coping with fertility issues among women with breast cancer. There is a growing demand for reliable tools to assess and enhance oncofertility support. This study aimed to validate a tool assessing oncofertility support.
methodsThe study involved two phases. First, insights from healthcare professionals and women with breast cancer were used to modify the Fertility Information Support Scale, resulting in a 22-item Oncofertility Support Scale. Second, a cross-sectional study was conducted among 343 participants aged 18-40 to assess the scale's content validity, structural validity, measurement invariance, convergent validity, known-group validity, and internal consistency reliability.
resultsExploratory factor analysis yielded a 19-item scale across four dimensions: information support on fertility impact, information support on fertility preservation, fertility and sexual guidance, and fertility communication and supportive networks. Confirmatory factor analysis confirmed the scale's structure. Multi-group confirmatory factor analysis showed measurement invariance across age and fertility desire groups. The content validity for the scale was 0.95. Oncofertility support showed a weak association with medical social support. Average Variance Extracted (AVE ≥ 0.63) and Composite Reliability (CR ≥ 0.90) supported the convergent validity of the scale. Women aged ≤ 30 reported higher information support on fertility preservation and fertility communication and supportive networks than those older than 30. Both Cronbach's alpha and McDonald's ω were 0.95.
conclusionThe Oncofertility Support Scale is a valid and reliable measure for assessing oncofertility support among women with breast cancer.
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