Evidence map›Paper›PMID 41419643›Full record

ArticleScientific reports2025

Circulating cell free HPVDNA in HPV positive head and neck cancer reveals fast responders and early peakers during treatment.

Mark Zupancic, Madeleine Birgersson, Ourania N Kostopoulou, Linda Marklund, Rusana Bark, Signe Friesland, Cecilia Jylhä, Emma Tham, Anders Näsman, Lars Sivars and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mark Zupancic *Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Madeleine Birgersson *Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Ourania N KostopoulouDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Linda MarklundMedical Unit Head, Neck, Lung, and Skin Cancer, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Rusana BarkMedical Unit Head, Neck, Lung, and Skin Cancer, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Signe FrieslandDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Cecilia JylhäDepartment of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
Emma ThamDepartment of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
Anders NäsmanDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Lars SivarsThe Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Tina DalianisDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden. Tina.Dalianis@ki.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of human papillomavirus-positive (HPV

Indexed as

Cell-Free Nucleic AcidsDNA, ViralHead and Neck NeoplasmsPapillomaviridaePapillomavirus InfectionsSquamous Cell Carcinoma of Head and NeckAdultAgedFemaleHumansMaleMiddle AgedTreatment OutcomeCell-Free Nucleic AcidsDNA, ViralBase of tongue cancerCancer of unknown primaryCell-free HPV DNACUPDigital droplet PCRHead and neck cancerHPVOropharyngeal cancerTonsillar cancer

Identifiers

PMID41419643
PMCPMC12722297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.