Evidence map›Paper›PMID 41419635›Full record

ArticleScientific reports2025

Identification of genetic variants associated with ear length in drop-eared dogs.

Tori E Rudolph, Anna R Ramey, Jonah N Cullen, Steven G Friedenberg, Leigh Anne Clark

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tori E RudolphDepartment of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Anna R RameyDepartment of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Jonah N CullenDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
Steven G FriedenbergDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
Leigh Anne ClarkDepartment of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA. laclark@uga.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

External ear size varies dramatically across animals, in part because of its role in thermoregulation: small ears conserve heat, while large ears dissipate heat. Genetic factors influencing ear size are known in several domesticated species but remain unexplored in dogs. We used whole-genome sequences aligned to canFam4 to perform an across-breed genome-wide association study (GWAS) for drop ear length. We identified a significant locus on canine chromosome (CFA) 10, intergenic to MSRB3 and HMGA2. The position of the lead variant (chr10:8,612,500, P = 1.85 × 10

Indexed as

EarGenetic VariationAllelesAnimalsDogsGenome-Wide Association StudyHaplotypesPolymorphism, Single NucleotideCanineEar carriageEar sizeGWASMSRB3

Identifiers

PMID41419635
PMCPMC12830694

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.