Observational studyScientific reports2025
Multivariate data analysis of sex differences in emotional and cognitive evaluations over 1 year after stroke.
Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
Post-stroke disabilities in cognition and mood lead to worse stroke recovery trajectory but are frequently overlooked. Although neurological factors and clinical history have been documented as important predictors of these invisible handicaps, the role of sex has not been given enough scrutiny. Examining sex-based differences in these outcomes could help deliver better post-stroke care. The goal of this study was to explore the interplay over one year between post-stroke cognitive and socio-affective assessments for men and women separately. Clinical evaluations of a monocentric hospital-based cohort including 263 patients with first-ever ischemic stroke were taken before hospital discharge and at 3- and 12-months post-stroke. Univariate comparisons between men and women were conducted, followed by multivariate analyses controlling for stroke severity, age, and education. Partial correlations between neuroradiological (stroke volume, white matter hyperintensities), cognitive (Montreal Cognitive Assessment test), mood (Hospital Anxiety and Depression scale; Apathy Inventory), and quality-of-life (Life Satisfaction Questionnaire-9) metrics were computed for both sexes. In multivariate analyses, women showed higher levels of baseline depression (p
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