ArticleScientific reports2025
Simultaneous determination of vitamin B12 and cobalt (II) in infant milk power using liquid chromatography-inductively coupled plasma mass spectrometry.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A new method was developed for simultaneous determination of cobalamin compounds [cyanocobalamin (CN-Cbl), hydroxocobalamin (OH-Cbl), 5'-deoxyadenosylcobalamin (Ado-Cbl) and methylcobalamin (Me-Cbl)] and inorganic cobalt ions [Co(II)] in infant milk powder by liquid chromatography-inductively coupled plasma mass spectrometry (LC-ICP-MS). The samples were enzymatic hydrolyzed by pepsin (porcine source) and the analytes extracted in the hydrolysate were measured directly by LC-ICP-MS after filtration. The chromatographic separation was performed on a Phenomenex Luna 5 μm C
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