Evidence map›Paper›PMID 41419379›Full record

Trial reportBritish journal of anaesthesia2026

Preoxygenation with high-flow nasal oxygen at various flow rates in elective surgical patients: a prospective, randomised, single-blind clinical trial.

Albin Sjöblom, Frida Hoffman, Magnus Hedberg, Ida-Maria Forsberg, Malin Jonsson Fagerlund

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in British journal of anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06736132 (Comparison of Different Oxygen Flow Rates During Preoxygenation Using High-Flow Nasal Oxygen), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06736132 naactive not recruitingnot on this map

Comparison of Different Oxygen Flow Rates During Preoxygenation Using High-Flow Nasal Oxygen

TypeinterventionalSponsorRegion StockholmRan2025 to 2026Enrolled75ConditionsAirway Anesthesia, Preoxygenation, High Flow Nasal CanulaArmsHigh-flow nasal oxygen
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Albin SjöblomKarolinska University Hospital, Stockholm, Sweden; Karolinska Institutet, Stockholm, Sweden. Electronic address: albin.sjoblom@ki.se.
Frida HoffmanKarolinska University Hospital, Stockholm, Sweden; Karolinska Institutet, Stockholm, Sweden.
Magnus HedbergKarolinska University Hospital, Stockholm, Sweden; Karolinska Institutet, Stockholm, Sweden.
Ida-Maria ForsbergKarolinska University Hospital, Stockholm, Sweden; Karolinska Institutet, Stockholm, Sweden.
Malin Jonsson FagerlundKarolinska University Hospital, Stockholm, Sweden; Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-flow nasal oxygen (HFNO) is increasingly used for preoxygenation. Previous studies of preoxygenation have explored flow rates below 60 L min

methodsThis randomised trial included patients aged 18-84 yr of ASA physical status 1-3 scheduled for elective surgery. Preoxygenation was conducted using HFNO at randomised flow rates of 45, 70, or 95 L min

resultsOf 72 participants included in the final analysis, baseline characteristics were similar and the mean duration of preoxygenation was 250 s in all three groups. Apnoea times did not differ, with median durations of 472, 523, and 483 s for 45, 70, and 95 L min

conclusionsThere was no difference in the safe apnoea time between preoxygenation with the three flow rates. As 45 L min CLINICAL

trial registrationNCT06736132.

Indexed as

Elective Surgical ProceduresOxygenOxygen Inhalation TherapyAdolescentAdultAgedAged, 80 and overApneaFemaleHumansMaleMiddle AgedOxygen SaturationProspective StudiesSingle-Blind MethodYoung AdultOxygenairway managementapnoeahigh-flow nasal oxygenhypercarbiaoxygenationpreoxygenationtracheal intubation

Identifiers

PMID41419379
PMCPMC12975348

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.