Evidence map›Paper›PMID 41419336›Full record

ArticleeNeuro2026

A DC-Sensitive Video/Electrophysiology Monitoring Unit for Long-Term Continuous Study of Seizures and Seizure-Associated Spreading Depolarization in a Rat Model.

Jiayang Liu, Bruce J Gluckman

Abstract read
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Tail-rattling in rodents: more than a threat display.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jiayang LiuCenter for Neural Engineering, Pennsylvania State University, University Park, Pennsylvania 16802 ljylxl@gmail.com.ORCID 0009-0001-1700-3203
Bruce J GluckmanCenter for Neural Engineering, Pennsylvania State University, University Park, Pennsylvania 16802.ORCID 0000-0001-7695-2225

Funding

CRCNS: Collaborative Research: State-Dependent Control for Brain ModulationR01EB014641 · NIBIB · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GLUCKMAN, BRUCE J, SCHIFF, STEVEN J · 2011 to 2021
$1.6M
CRCNS: Model Based Data Assimilation & Control of Sleep-Wake Regulation in EpilepsyR01EB019804 · NIBIB · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI ALLOWAY, KEVIN DOUGLAS, GLUCKMAN, BRUCE J · 2014 to 2017
$1.2M
NIBIB NIH HHS R01 EB014641NIBIB NIH HHS R01 EB019804
6 · The paper itself

Abstract

There has been a long-term need for a low-cost, highly efficient, and high-fidelity epilepsy monitoring unit (EMU) suitable for synchronized multimodal home-cage monitoring of small-animal models of epilepsy and spreading depolarization. We present an accessible, scalable, highly space- and energy-efficient EMU capable of fulfilling chronic, continuous, synchronized, multiple-animal monitoring jobs. Each rig within the EMU can provide 16-channel high-fidelity, DC-sensitive biopotential recordings, head acceleration monitoring, voltammetry applications, and synchronized video recording on one freely moving rat. We present the overall EMU architecture design and subsystem details in each recording rig. We demonstrate long-term continuous in vivo recordings of spontaneous seizure and seizure-associated spreading depolarization from freely moving rats (male, 21; female, 6) prepared under the tetanus toxin model of temporal lobe epilepsy.

Indexed as

Cortical Spreading DepressionEpilepsy, Temporal LobeNeurophysiological MonitoringSeizuresVideo RecordingAnimalsDisease Models, AnimalElectroencephalographyFemaleMaleRatsRats, Sprague-Dawleyepilepsy monitoring unitfreely moving animallong-term recordingspontaneous seizurespreading depolarizationtissue oxygenation

Identifiers

PMID41419336
PMCPMC12834326

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.