Evidence map›Paper›PMID 41419313›Full record

ReviewCold Spring Harbor perspectives in biology2026

Mitochondrial Calcium Signaling in Hepatocyte Health and Disease.

David R Eberhardt, Dipayan Chaudhuri

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David R EberhardtNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah 84132, USA.
Dipayan ChaudhuriNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah 84132, USA dipayan.chaudhuri@hsc.utah.edu.ORCID 0000-0003-0605-7334

Funding

Metabolic Impact and Mechanism of Enhanced Mitochondrial Calcium Uptake in Mitochondrial CardiomyopathiesR01HL141353 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Dipayan Chaudhuri · 2018 to 2026
$4.3M
Regulation of the mitochondrial calcium uniporterR01HL165797 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Dipayan Chaudhuri · 2022 to 2026
$2.5M
Mechanisms of mitochondria-driven hepatocyte injuryR01DK141142 · NIDDK · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Dipayan Chaudhuri · 2025 to 2026
$1.5M
Structural basis for mitochondrial calcium uniporter functionR00HL124070 · NHLBI · UNIVERSITY OF UTAH · PI CHAUDHURI, DIPAYAN · 2016 to 2018
$747k
Structural basis for mitochondrial calcium uniporter functionK99HL124070 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI CHAUDHURI, DIPAYAN · 2014 to 2015
$292k
NHLBI NIH HHS K99 HL124070NHLBI NIH HHS R00 HL124070NHLBI NIH HHS R01 HL141353NHLBI NIH HHS R01 HL165797NIDDK NIH HHS R01 DK141142
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

Calcium SignalingHepatocytesLiver DiseasesMitochondriaMitochondria, LiverAnimalsCalciumHumansCalcium

Identifiers

PMID41419313
PMCPMC12815592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.