ArticleEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists2026
Role of Glycemia, Vitamin D, and Physical Activity in Bone Mineral Density in Youth With Type 1 Diabetes.
Article in Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesTo evaluate bone mineral density (BMD) and identify factors associated with BMD in youth with type 1 diabetes (T1D)
methodsThis cross-sectional study included youth aged 8-17 years with T1D for ≥1 year. BMD was assessed using dual-energy x-ray absorptiometry. T1D-related data, anthropometrics, 25-hydroxyvitamin D (25OHD), and weight-bearing activities were analyzed.
resultsOne hundred twenty-four youth participated, with mean age 12.9 ± 2.5 years, diabetes duration 6.0 ± 3.2 years, body mass index (BMI) z-score 0.67 ± 0.81, hemoglobin A1c 8.1 ± 1.1%, glucose time-in-range (TIR) 49.1 ± 17.2%, glucose coefficient of variation (CV) 41.2 ± 7.5%, total daily insulin dose 0.9 ± 0.3 units/kg, 25OHD 29.4 ± 8.6 ng/mL, and energy expenditure from high-impact weight-bearing activities 215 ± 358 kcal/24 h; 73% used insulin pumps, 9% were vitamin D-deficient; 51% engaged in high-impact weight-bearing activities. Mean BMD z-score was -0.2 ± 1.0, lower than pediatric normative data (P = .007). BMD z-scores correlated with BMI z-scores (r = 0.32, P = .0002), TIR (r = 0.24, P = .007), 25OHD (r = 0.22, P = .01), and energy expenditure from high-impact weight-bearing activities (r = 0.20, P = .03). Vitamin D-deficient group had lower BMD z-scores (Δ0.7, P = .02). Those engaging in high-impact weight-bearing activities had higher BMD z-scores (Δ0.3, P = .03). No associations were found with diabetes duration, total daily insulin dose, pump use, or CV.
conclusionsYouth with T1D have slightly lower BMD compared with pediatric norms. Optimizing BMI, TIR, vitamin D, and high-impact weight-bearing activities may improve bone health in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.