Evidence map›Paper›PMID 41418784›Full record

ReviewStem cell reports2026

Pluripotent stem cell lines available for use in clinical applications: A comprehensive overview.

Melissa K Carpenter, Tenneille E Ludwig

Erratum issuedAbstract readReview
In one paragraph

Review in Stem cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Melissa K CarpenterCarpenter Consulting Corporation, Bellingham, WA, USA. Electronic address: melissa@carpentergroupstrategy.com.
Tenneille E LudwigWiCell Research Institute, Madison, WI, USA; University of Wisconsin-Madison Stem Cell and Regenerative Medicine Center, Madison, WI, USA. Electronic address: tludwig@wicell.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last 25 years, there has been tremendous progress in human pluripotent stem cell (hPSC) technology and clinical trials testing hPSC-derived products. The development of these hPSC-derived products requires the selection of a suitable hPSC line as the starting material for product manufacturing. The bespoke development of an hPSC line for product development can require significant time and resources. Given the acceleration of clinical trials testing hPSC-derived products, there is a growing need for available clinically and commercially suitable "off-the-shelf" hPSC lines. We have identified 166 clinical hPSC lines that are currently available for licensing and distribution. This paper provides details regarding these lines that may assist developers in preliminary evaluation of lines for use in clinical development.

Indexed as

Pluripotent Stem CellsCell DifferentiationCell LineHumansclinical hESCclinical hiPSCGMPinformed consentquality systems

Identifiers

PMID41418784
PMCPMC12925947

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.