ArticleInternational journal of surgery (London, England)2026
Ectopic parathyroid adenomas in primary hyperparathyroidism: anatomical classifications, localization strategies, and case series.
Article in International journal of surgery (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEctopic parathyroid adenomas (EPAs) pose significant challenges in the diagnosis and management of primary hyperparathyroidism (PHPT) due to their atypical locations. This study aims to categorize EPAs based on their anatomical locations, describe the associated diagnostic strategies, and present case studies to illustrate clinical management.
methodsEPAs were retrospectively reviewed based on cases from published literature and our institutional experience. Relevant studies were identified through a systematic search of PubMed and Embase. A comprehensive anatomical classification system was developed, categorizing EPAs into pharyngocranial, cervical, and mediastinal regions.
resultsFrom a total of 1278 screened publications, 137 studies encompassing 875 EPAs were identified and included. Combined with 13 original cases from our institute, these cases were comprehensively analyzed to develop an anatomically based classification system. EPAs were categorized into four types based on anatomical location: Type I (pharyngocranial), Type II (cervical, adjacent to the thyroid), Type III (cervical, distant from the thyroid), and Type IV (mediastinal). A combination of imaging modalities, including ultrasonography, CT, MRI, sestamibi scintigraphy, and SPECT, proved effective for preoperative localization. Case studies highlight clinical outcomes and challenges associated with each type.
conclusionA comprehensive anatomical classification system for EPAs, integrated with advanced imaging modalities and correlated with biochemical profiles, improves preoperative identification and guides targeted treatment strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.