ArticlePloS one2025
Impact of adherence and stringency on the effectiveness of lockdown measures: A modelling study.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Mechanics of pandemics.EClinicalMedicine · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the COVID-19 pandemic, lockdowns were a widely used strategy to reduce disease transmission. However, there was much debate about the optimal level of strictness and duration of lockdowns. This study considers how lockdowns impact public health opinions, which in turn influence adherence to and effectiveness of these measures. We developed an agent-based simulation model to theoretically explore the impact of health-related opinions on the effectiveness of lockdowns in controlling disease spread. We simulated these dynamics within a hypothetical population connected via a simplified contact network (Watts-Strogatz), incorporating feedback loops between disease prevalence, opinions, and behaviour, including 'lockdown fatigue'. We explored different scenarios of lockdown implementation in our hypothetical population network by varying a threshold value of prevalence when a lockdown is initiated and the stringency of the lockdown. Our qualitative findings imply that quickly imposing a lockdown with high stringency is the most effective at reducing infection spread, provided that there is a certain degree of adherence to the lockdown among the population. Furthermore, stricter lockdowns minimize fatigue with respect to the imposed measures, since the duration of a lockdown is shorter on average in this scenario. These theoretical results imply that such lockdown policies might therefore be a beneficial, high-impact tool in containing epidemic spread, especially when supplemented by information interventions maintaining the adherence to lockdown measures.
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Registered trials
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