ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy.
Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
As essential functional components of the cell membrane, membrane proteins serve as one of the key mechanisms for sensing external stimuli and play crucial roles in diverse biological processes, including cell migration, proliferation, differentiation, and apoptosis. These processes are closely related to the maintenance of physiological homeostasis and the progression of various diseases. In recent years, with an in-depth understanding of membrane protein functions, developing membrane protein regulation strategies has emerged as a significant direction in both basic research and therapeutic applications. Precise modulation of membrane protein expression levels, conformational changes, and spatial distribution enables artificial regulation of cellular behavior, thereby opening promising avenues for treating diseases such as cancer, neurodegenerative disorders, and immune dysfunctions. This review comprehensively summarizes various physical technologies and biomolecule-driven approaches for membrane protein regulation, including applying light/temperature/magnetism/ultrasound-sensitive modules to achieve external physical control, as well as biomolecular tools, such as DNA, peptides, and proteins with specific receptor recognition properties that modulate membrane proteins via intermolecular interactions. Furthermore, the advantages and limitations of different membrane protein regulation techniques are discussed, aiming to provide new insights into cell function regulation and disease treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.