ArticleJournal of chemical information and modeling2026
Interaction of Carbon Dots with Nucleic Acids Is Driven by Their Surface Charge.
Article in Journal of chemical information and modeling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon dots (CDs) are nanoscale carbon materials with tunable optical properties, low toxicity, and modular functionalization, making them a promising material for biomedical applications. For safe and efficient applications in theranostics, it is essential to assess how CDs interact with biomolecules. Here, we focus on the effect of CDs on the structure and function of nucleic acids (NAs), relevant to NA structural stability, chromatin organization, and gene regulation. We performed more than 150 μs of atomistic molecular dynamics simulations, encompassing a diverse set of NA structures, from canonical DNA and RNA helices through noncanonical motifs such as tetraloops and G-quadruplexes, up to nucleosomes. We simulated their interactions with graphitic CDs with two sizes and distinct surface chemistries: neutral hydrophobic (CD
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Registered trials
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