Evidence map›Paper›PMID 41417577›Full record

ArticleRevista medica del Instituto Mexicano del Seguro Social2026

[Multisystem inflammatory syndrome in a young infant with lymphocytosis and reactive thrombocytosis post COVID-19: Case report].

Hannia Andrea Vera-Rodríguez, Lenyn Daniel Montes-Sevilla, Víctor Itzcóatl González-Maturano, José Roberto Pioquinto-Mendoza, Patricia Cabrera-Morales

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Revista medica del Instituto Mexicano del Seguro Social, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Hannia Andrea Vera-RodríguezUniversidad Autónoma del Estado de Hidalgo, Instituto de Ciencias de la Salud. Pachuca, Hidalgo, México.ORCID 0009-0009-7049-6746
Lenyn Daniel Montes-SevillaSecretaría de Salud, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Cirugía General. Ciudad de México, México.ORCID 0009-0009-7049-6746
Víctor Itzcóatl González-MaturanoUniversidad Autónoma del Estado de Hidalgo, Instituto de Ciencias de la Salud. Pachuca, Hidalgo, México.ORCID 0009-0002-7343-3547
José Roberto Pioquinto-MendozaHospital del Niño DIF, Coordinación de Enseñanza e Investigación. Pachuca, Hidalgo, México.ORCID 0000-0002-2903-6125
Patricia Cabrera-MoralesHospital del Niño DIF, Subdirección Médica, Especialidad en Infectología Pediátrica. Pachuca, Hidalgo, México.ORCID 0000-0002-0199-8496

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multisystem inflammatory syndrome in children (MIS-C) is a rare, but serious complication associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, characterized by persistent fever, systemic inflammation, and multiorgan involvement. It predominantly affects school-aged children and adolescents. Reports in infants under 1 year are limited, and atypical presentations pose diagnostic challenges. Clinical case: 8-month-old male infant who presented with 10 days of persistent fever, diarrhea, and irritability. Initial laboratory findings revealed leukocytosis, marked thrombocytosis, persistent lymphocytosis, and significantly elevated liver enzymes. No mucocutaneous findings or cardiac involvement were noted. The diagnosis of MIS-C was established based on Centers for Disease Control and Prevention (CDC) criteria and confirmed by positive IgG serology for SARS-CoV-2. Treatment with intravenous immunoglobulin (IVIg), aspirin, and corticosteroids achieved a favorable clinical and biochemical evolution. Conclusions: This case highlights an atypical presentation of MIS-C in a young infant, with hematological findings that differ from classic patterns. Early recognition and standard immunomodulatory therapy led to a successful outcome. Documenting such variants is essential to expand our understanding of MIS-C in underrepresented age groups.

Indexed as

COVID-19LymphocytosisSystemic Inflammatory Response SyndromeThrombocytosisHumansImmunoglobulins, IntravenousInfantMaleImmunoglobulins, IntravenousCOVID-19Infant HealthLinfocitosisLymphocytosisMucocutaneous Lymph Node SyndromeSalud del LactanteSíndrome Mucocutáneo LinfonodularThrombocytosisTrombocitosis

Identifiers

PMID41417577
PMCPMC12774440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.