Evidence map›Paper›PMID 41417546›Full record

ArticleArquivos brasileiros de cardiologia2025

The Cost of Medical Management in Advanced Heart Failure: A Latin American Perspective.

Livia Adams Goldraich, Ana Paula Beck da Silva Etges, Laura Caroline Tavares Hastenteufel, Dayanna Machado Lemos, Andreas Zuckermann, Mandeep R Mehra, Carisi Anne Polanczyk, Nadine Clausell

Abstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Livia Adams GoldraichPrograma de Insuficiência Cardíaca Avançada e Transplante Cardíaco, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS - Brasil.ORCID 0000-0002-1523-4286
Ana Paula Beck da Silva EtgesInstituto Nacional de Ciência e Tecnologia para Avaliação de Tecnologias em Saúde e Conselho Nacional de Desenvolvimento Científico e Tecnológico, Porto Alegre, RS - Brasil.
Laura Caroline Tavares HastenteufelPrograma de Insuficiência Cardíaca Avançada e Transplante Cardíaco, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS - Brasil.ORCID 0000-0003-2022-7512
Dayanna Machado LemosPrograma de Insuficiência Cardíaca Avançada e Transplante Cardíaco, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS - Brasil.
Andreas ZuckermannDepartment of Cardiac Surgery, Medical University of Vienna, Vienna - Áustria.
Mandeep R MehraBrigham and Women's Hospital and Harvard Medical School, Boston, MA - EUA.ORCID 0000-0001-8683-7044
Carisi Anne PolanczykPrograma de Insuficiência Cardíaca Avançada e Transplante Cardíaco, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS - Brasil.
Nadine ClausellPrograma de Insuficiência Cardíaca Avançada e Transplante Cardíaco, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS - Brasil.ORCID 0000-0003-4207-3809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe financial burden faced by patients with advanced heart failure (HF) who are ineligible for heart transplantation or lack have access to advanced therapy with left ventricular assist devices (LVADs) has not been described in Latin American.

objectiveTo conduct a microcosting study in patients who were otherwise eligible for LVAD therapy who did not have access to it.

methodsWe evaluated the direct costs of care in a cohort of advanced HF patients treated at a Brazilian public hospital who were candidates for LVAD therapy (and ineligible for transplantation) but lacked access to the procedure. A patient-level cost analysis was performed from the time LVAD need was identified until death or end of follow-up. The total cost per patient was calculated using the time-driven activity-based costing methodology and expressed in international dollars (Int$). Patients were stratified by disease severity and all-cause mortality to assess cost variability.

resultsFigure 2.

conclusionsThis study highlights the financial burden associated with ongoing medical management of advanced HF in patients who would otherwise be eligible for LVAD therapy. These findings provide a basis for evaluating the cost-effectiveness of device-based, life-saving interventions in selected advanced HF populations.

Indexed as

Health Care CostsHeart-Assist DevicesHeart FailureAgedBrazilCost-Benefit AnalysisCost of IllnessFemaleHumansLatin AmericaMaleMiddle AgedSeverity of Illness IndexTime Factors

Identifiers

PMID41417546
PMCPMC12711218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.