Evidence map›Paper›PMID 41417471›Full record

ArticleChemistry & biodiversity2026

Seasonality Affects the Phenolic Composition and Erythroprotective Activity of Ora-Pro-Nobis (Pereskia aculeata) Leaves.

Thiago Mendanha Cruz, Cristiane de Moura, Daniel Granato, Mariza Boscacci Marques

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thiago Mendanha CruzGraduation Program in Chemistry, State University of Ponta Grossa, Av. Carlos Cavalcanti, Ponta Grossa, Brazil.ORCID https://orcid.org/0000-0003-2287-7439
Cristiane de MouraGraduation Program in Chemistry, State University of Ponta Grossa, Av. Carlos Cavalcanti, Ponta Grossa, Brazil.
Daniel GranatoDepartment of Food Science and Microbiology, Auckland University of Technology, Auckland, New Zealand.
Mariza Boscacci MarquesGraduation Program in Chemistry, State University of Ponta Grossa, Av. Carlos Cavalcanti, Ponta Grossa, Brazil.ORCID https://orcid.org/0000-0002-6225-5258

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ora-pro-nobis (OPN) is a food plant with polyphenol-rich leaves. However, the influence of seasonality on their quantitative phenolic composition and how it impacts their bioactivities is unknown. OPN leaves were harvested throughout 12 months, and their individual phenolic content, antioxidant activity, and erythroprotection were assessed. The highest total phenolic content was recorded in September (736 mg GAE/100 g), and the lowest in October (104 mg GAE/100 g). September also exhibited the highest rutin and protocatechuic, p-coumaric, and caffeic acids concentrations. Rutin was the major compound throughout the year. Protocatechuic acid contents were correlated with the air relative humidity, solar radiation incidence, and air temperature. June sample presented the best 2,2-diphenyl-1-picrylhydrazyl scavenging activity (227 mg AAE/100 g), while August was the most efficient sample to Fe

Indexed as

AntioxidantsErythrocytesPhenolsPlant ExtractsPlant LeavesSeasonsBiphenyl CompoundsHumansPicrates1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsPhenolsPicratesPlant Extractsantioxidant capacityCactaceaeharvest timeoxidative stressprotein oxidation

Identifiers

PMID41417471
PMCPMC12860515

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.