Evidence map›Paper›PMID 41417437›Full record

ArticleAging clinical and experimental research2025

Prevalence and influencing factors of dementia in the elderly iranian population: a cross-sectional study.

Esmat Karimian, Afrooz Saffari Fard, Mehri Golparvar, Hossein Khodaei, Masoumeh Salehi, Gholamreza Hajati, Fatemeh Khamseh, Farshad Sharifi, Yousef Veisani

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Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Esmat KarimianPrevention of Disabilities and Social Integration, State Welfare Organization, Tehran, Iran.
Afrooz Saffari FardPrevention of Disabilities and Social Integration, State Welfare Organization, Tehran, Iran.
Mehri GolparvarPrevention of Disabilities and Social Integration, State Welfare Organization, Ghazvin, Iran.
Hossein KhodaeiPrevention of Disabilities and Social Integration, State Welfare Organization, Yazd, Iran.
Masoumeh SalehiIran Dementia & Alzheimer's Association (IDAA), Tehran, Iran.
Gholamreza HajatiIran Dementia & Alzheimer's Association (IDAA), Tehran, Iran.
Fatemeh KhamsehIran Dementia & Alzheimer's Association (IDAA), Tehran, Iran.
Farshad SharifiElderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Yousef VeisaniNon-Communicable Diseases Research Center, Ilam University of Medical Sciences, PO Box, Ilam, 69311-63545, Iran. yousefveisani@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global rise in dementia prevalence, a major neurocognitive disorder, poses a significant challenge to aging populations. This study aimed to determine the prevalence of dementia and its associated risk factors among community-dwelling elderly in selected provinces of Iran.

methodsA cross-sectional study was conducted from October 2022 to March 2024, enrolling 58,228 individuals aged 60-75 years from two provinces (Qazvin and Yazd) selected via multi-stage, stratified random sampling. A multi-stage diagnostic protocol was employed, using validated Persian versions of the Geriatric Depression Scale (GDS), Abbreviated Mental Test Score (AMTS), Mini-Mental State Examination (MMSE), Functional Assessment Staging (FAST), and Montreal Cognitive Assessment (MoCA) with standardized cut-offs. Multivariable logistic regression was used to identify factors associated with dementia.

resultsAfter exclusions, the final analytical sample was 56,456 participants. The overall prevalence of dementia was 10.1%. Prevalence was significantly higher in women (13.2%) than in men (7.0%). In the adjusted model, female gender (aOR: 2.04, 95% CI: 1.92-2.15), older age (70-79 years vs. 60-64 years, aOR: 1.70, 95% CI: 1.59-1.82), widowhood (aOR: 1.50, 95% CI: 1.05-2.16), and lower educational attainment (illiterate vs. academic, aOR: 6.55, 95% CI: 5.43-7.91) were significantly associated with higher odds of dementia.

conclusionsThis large-scale study reveals a substantial burden of dementia in the studied Iranian provinces. The identified risk factors, including female sex, advanced age, widowhood, and low education, highlight vulnerable subgroups and underscore the urgent need for targeted public health strategies focused on early detection, risk reduction, and support systems for the elderly in Iran.

Indexed as

DementiaAgedCross-Sectional StudiesFemaleHumansIranMaleMental Status and Dementia TestsMiddle AgedPrevalenceRisk FactorsAgingCognitive ReserveDementiaEpidemiologyIranRisk Factors

Identifiers

PMID41417437
PMCPMC12775042

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.