Evidence map›Paper›PMID 41417430›Full record

ArticleDiscover oncology2025

Bibliometric analysis of global research on liquid biopsy for gastric cancer.

Huazhen Zheng, Peng Wang, Huijie Zheng, Feiwen Deng, Yifan Xv, Huanwei Chen, Zhenling Ji, Huoqiang Chen, Qiucheng Lei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huazhen Zheng *Department of Clinical Laboratory, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
Peng Wang *Department of Gastrointestinal surgery, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
Huijie ZhengDepartment of Clinical Laboratory, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
Feiwen DengDepartment of Hepatopancreatic Surgery, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
Yifan XvSchool of Medicine, Southeast University, Nanjing, Jiangsu, China.
Huanwei ChenDepartment of Hepatopancreatic Surgery, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
Zhenling JiSchool of Medicine, Southeast University, Nanjing, Jiangsu, China.
Huoqiang ChenDepartment of Clinical Laboratory, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China.
Qiucheng LeiDepartment of Hepatopancreatic Surgery, The First People's Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, Foshan, Guangdong, China. lqiuchenggd@163.com.

Funding

The National Natural Science Foundation of China 82400651The Science and Technology Innovation Project of Foshan 2320001006781
6 · The paper itself

Abstract

backgroundGastric cancer (GC) is one of the most common malignant tumors worldwide, with a poor overall survival rate. Liquid biopsy (LB) is a non-invasive approach that can assist with the diagnosis and dynamic monitoring of GC. The aim of this study is to use bibliometric analysis to evaluate global trends in LB of GC from 2000 to 2025 and visualise the frontiers.

methodsA literature search was conducted on Web of Science for studies on LB in GC published between 2000 and 2025. The retrieved articles were analysed using descriptive statistics and visualisation to examine the annual publication number, prolific countries and institutions, influential authors and journals, and the number of citations.

resultsA total of 360 publications were identified, showing consistent growth in output from 2002 to 2025, with a notable acceleration around 2016. Ichikawa D was the most prolific author, contributing 8 publications and amassing 338 citations, which highlights his significant academic impact. China led in terms of publication output with 146 publications, followed closely by the USA and Japan. Journals such as Cancers and Frontiers in Oncology occupied central positions in the network, reflecting their interdisciplinary significance. Frequent key terms such as LB, GC, biomarker and circulating tumour DNA (ctDNA) emphasised the focus on diagnostic applications and molecular targets in research.

conclusionsThe field of liquid biopsy for GC is entering a period of rapid development. This bibliometric analysis maps the fundamental knowledge structure of this field. The hotspots identified in this study warrant further investigation.

Indexed as

Bibliometric analysisCiteSpaceCtDNAGastric cancerLiquid biopsy

Identifiers

PMID41417430
PMCPMC12728139

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.