ArticleRevista da Associacao Medica Brasileira (1992)2025
Assessing Chat Generative Pretrained Transformer-4's clinical utility in acute compartment syndrome: a comprehensive evaluation of accuracy, completeness, and readability.
Article in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prostate cancer research on social media platforms: a bibliometric and thematic analysis.Frontiers in oncology · 2026Pooled it
- Comment on "Assessing Chat Generative Pretrained Transformer-4's clinical utility in acute compartment syndrome: a comprehensive evaluation of accuracy, completeness, and readability".Revista da Associacao Medica Brasileira (1992) · 2026Article
- Comment on "Assessing Chat Generative Pretrained Transformer- 4's clinical utility in acute compartment syndrome: a comprehensive evaluation of accuracy, completeness, and readability".Revista da Associacao Medica Brasileira (1992) · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveArtificial intelligence tools like Chat Generative Pretrained Transformer-4 are increasingly used in clinical decision-making, but their reliability for acute compartment syndrome remains understudied. The aim of the study was to evaluate Chat Generative Pretrained Transformer-4's accuracy, completeness, and quality in responding to acute compartment syndrome-related queries, addressing gaps in artificial intelligence-assisted medical information.
methodsChat Generative Pretrained Transformer-4 was given 60 questions (40 open-ended and 20 binary) that were taken from the American Academy of Orthopaedic Surgeons 2019 acute compartment syndrome guidelines. Responses were evaluated independently by two orthopedic specialists using the Quality Criteria for Consumer Health Information instrument (information quality), Flesch-Kincaid Reading Ease Score (readability), and Likert scales (accuracy and completeness). Inter-rater reliability (Cohen's kappa) was a statistical analysis.
resultsChat Generative Pretrained Transformer-4 demonstrated high accuracy (95% for both question types) and completeness (mean scores: 5.92±0.8 [accuracy], 2.9±0.5 [completeness]). DISCERN scores were "excellent" (69-72), though source reliability was limited. Readability was "very difficult" (Flesch-Kincaid Reading Ease Score: 22.19), potentially hindering patient comprehension.
conclusionAlthough Chat Generative Pretrained Transformer-4 is excellent at providing precise, high-quality acute compartment syndrome information, its complicated language and lack of credible sources make it difficult for wider adoption. To improve clinical utility and patient education, readability and transparency must be given top priority in future artificial intelligence developments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.