SynthesisRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2025
Impacts of COVID-19 on pediatric patients with congenital heart disease: a small systematic and integrative literature review.
Synthesis in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
objectiveThe objective of this study was to compile primary studies to understand the impacts of COVID-19 on pediatric patients with congenital heart disease. DATA SOURCE: A systematic review based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) method, with searches conducted in the PubMed, Latin American and Caribbean Health Sciences Literature (LILACS), and Scientific Electronic Library Online (SciELO) databases. Studies published in the last 5 years, open access, and addressing the research question, "What are the main impacts of COVID-19 on pediatric patients with congenital heart disease?" were included. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS) and the Joanna Briggs Institute (JBI) tools. DATA SYNTHESIS: A total of 377 articles were identified, of which 12 met the inclusion criteria. The NOS tool indicated that two of the eight cohort studies had a risk of bias and lower methodological quality. The JBI tool revealed that three of the four cross-sectional studies had a low risk of bias and good methodological quality. The integrative analysis highlighted three main impacts of COVID-19 on these patients: difficulties in follow-up and treatment, reduced physical activity due to social distancing, and postponement of procedures and surgeries. Infected patients experienced increased complications and hospitalizations, but without a significant change in mortality.
conclusionsThe COVID-19 pandemic significantly affected the health and management of congenital heart disease, leading to clinical complications and worsening follow-up. Further primary and secondary studies are needed to strengthen the evidence and improve patient management.
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