Evidence map›Paper›PMID 41417301›Full record

ArticleArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2025

Preoperative glycemic response to a very low-calorie diet predicts long-term type 2 diabetes remission after bariatric surgery.

Mariana Fior Frias Thomaz Bortolan, Roberto DE Cleva, Leandro Ferreira, Denis Pajecki, Marco Aurelio Santo

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Article in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mariana Fior Frias Thomaz BortolanUniversidade de São Paulo, Faculty of Medicine, Science Program in Gastroenterology - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0003-7312-8339
Roberto DE ClevaUniversidade de São Paulo, Faculty of Medicine, Department of Gastroenterology - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0001-8673-9014
Leandro FerreiraUniversidade de São Paulo, Faculty of Medicine, Department of Gastroenterology - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-1439-1941
Denis PajeckiUniversidade de São Paulo, Faculty of Medicine, Department of Gastroenterology - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-0898-9285
Marco Aurelio SantoUniversidade de São Paulo, Faculty of Medicine, Department of Gastroenterology - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-7813-6210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity and type 2 diabetes mellitus are highly prevalent conditions with a significant public health impact, highlighting the need for effective management strategies. Bariatric surgery is widely recognized for promoting sustained weight loss and high rates of type 2 diabetes mellitus remission.

aimsThis study investigated the preoperative blood glucose response to a very low-calorie diet as a functional predictor of type 2 diabetes mellitus remission following Roux-en-Y gastric bypass.

methods198 participants who followed a very low-calorie diet (600 kcal/day) during the preoperative period were included, with glycemic response monitoring.

resultsComplete remission of type 2 diabetes mellitus occurred in 66.7% of patients. Two years after surgery, patients with blood glucose levels below 143 mg/dL on the second day of the very low-calorie diet had a higher likelihood (over 70%) of achieving complete remission type 2 diabetes mellitus in the late postoperative period.

conclusionsPreoperative capillary blood glucose levels demonstrated good specificity in predicting remissions. These findings reinforce the clinical utility of early glycemic control as a valuable indicator for predicting the success of surgical treatment for type 2 diabetes mellitus.

Indexed as

Bariatric SurgeryBlood GlucoseCaloric RestrictionDiabetes Mellitus, Type 2Gastric BypassAdultFemaleHumansMaleMiddle AgedPreoperative CarePreoperative PeriodRemission InductionTime FactorsBlood Glucose

Identifiers

PMID41417301
PMCPMC12711146

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.