Evidence map›Paper›PMID 41417236›Full record

Trial reportEuropean journal of nutrition2025

Assessment of vitamin A, vitamin B

Tim Zerback, Christian Koeder, Stine Weder, Andreas Sputtek, Gunter P Eckert, Markus Keller

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tim ZerbackResearch Institute for Plant-Based Nutrition, 35444, Biebertal, Germany.ORCID http://orcid.org/0009-0003-0743-5736
Christian KoederInstitute for Prevention and Cancer Epidemiology (IPE), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79110, Freiburg im Breisgau, Germany. christiankoeder@gmail.com.ORCID http://orcid.org/0000-0002-3761-4220
Stine WederResearch Institute for Plant-Based Nutrition, 35444, Biebertal, Germany.ORCID http://orcid.org/0000-0001-5360-1940
Andreas SputtekMVZ Medical Laboratory Bremen GmbH, 28359, Bremen, Germany.
Gunter P EckertInstitute of Nutritional Sciences, Justus-Liebig University, 35392, Giessen, Germany.ORCID http://orcid.org/0000-0002-8002-9983
Markus KellerResearch Institute for Plant-Based Nutrition, 35444, Biebertal, Germany.ORCID http://orcid.org/0000-0001-5789-6280

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the MultiVeg study, a double-blind, randomised controlled trial (RCT), was to investigate the nutritional status of healthy vegans following 4 months of multinutrient supplementation.

methodsA double-blind, RCT was conducted with 72 vegan adults (19-57 years) in Germany. Data on anthropometric parameters, dietary nutrient intake, and nutritional status were collected. The nutritional status of the participants was assessed at baseline and after 4 months. The results were compared between groups using ANCOVA. The results for vitamins and choline are presented here.

resultsAfter adjustment for baseline values, age, sex, and multiple testing, no significant between-group differences in biomarker concentration changes from baseline to 4 months were observed for vitamin A, retinol-binding protein, transthyretin, beta-carotene, methylmalonic acid, homocysteine, choline, total osteocalcin, carboxylated and undercarboxylated osteocalcin, and folate. In contrast, significant between-group differences in changes were observed for flavin adenine dinucleotide (FAD), serum vitamin B

conclusionA multinutrient supplement containing 82 µg of vitamin B REGISTRATION: This study was registered in the German Clinical Trials Register (DRKS00028151).

Indexed as

CholineDietary SupplementsMicronutrientsNutritional StatusVegansAdultBiomarkersDouble-Blind MethodFemaleFolic AcidGermanyHumansMaleMiddle AgedRiboflavinVitamin ABiomarkersCholineFolic AcidMicronutrientsRiboflavinVitamin AVitamin B 12Vitamin KCobalaminMultinutrientRiboflavinVegan dietVitamin AVitamin K2

Identifiers

PMID41417236
PMCPMC12717231

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.