Evidence map›Paper›PMID 41417172›Full record

ArticleJournal of behavioral medicine2026

Application of the random-intercept cross-lagged panel model to behavioral intervention outcomes: a methodological tutorial assessing model fit.

Julián D Moreno-Villamizar, Daniel A Teplow, Qimin Liu, Laura Long, Daniella Spencer-Laitt, Mikaela de Lemos, Todd J Farchione

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julián D Moreno-VillamizarDepartment of Psychological and Brain Sciences, Center for Anxiety and Related Disorders, Boston University, Boston, USA. jdmoreno@bu.edu.ORCID 0009-0004-0910-0793
Daniel A TeplowDepartment of Psychological and Brain Sciences, Center for Anxiety and Related Disorders, Boston University, Boston, USA.ORCID 0009-0008-9115-8896
Qimin LiuDepartment of Psychological and Brain Sciences, Center for Anxiety and Related Disorders, Boston University, Boston, USA.ORCID 0000-0003-3840-1136
Laura LongDepartment of Psychological and Brain Sciences, Center for Anxiety and Related Disorders, Boston University, Boston, USA.ORCID 0000-0002-3409-4880
Daniella Spencer-LaittDepartment of Psychological and Brain Sciences, Center for Anxiety and Related Disorders, Boston University, Boston, USA.ORCID 0009-0002-9949-7848
Mikaela de LemosDepartment of Psychological and Brain Sciences, Center for Anxiety and Related Disorders, Boston University, Boston, USA.ORCID 0009-0005-9058-6619
Todd J FarchioneDepartment of Psychological and Brain Sciences, Center for Anxiety and Related Disorders, Boston University, Boston, USA.ORCID 0000-0002-6494-6829

Funding

John Templeton Foundation 61603
6 · The paper itself

Abstract

The Random-Intercept Cross-Lagged Panel Model (RICLPM) has gained popularity in longitudinal research due to its ability to disaggregate within- and between-subjects variance. This approach more accurately depicts processes over time compared to traditional Cross-Lagged Panel Models (CLPMs). While RICLPMs are increasingly used, their application to data from behavioral interventions still is underexplored. This study aims to address this gap by demonstrating the application of RICLPM using data from a clinical trial of the digital Unified Protocol (iUP), a transdiagnostic cognitive-behavioral intervention applicable to mental and physical health comorbidities. We focus specifically on how RICLPM can be used to examine dynamic psychological processes during treatment, a central yet under-addressed question in behavioral medicine. We provide a methodological tutorial on adapting the model to intervention outcomes data, compare model fit statistics from an RICLPM and a traditional CLPM, and interpret results specifically in the context of psychological processes during a cognitive-behavioral intervention. Our findings show that RICLPM offers superior fit and more precise estimates of within-subject processes, underscoring its value in clinical research. We argue that adopting RICLPM in behavioral medicine research can help accurately identify psychological mechanisms and processes during behavioral interventions in health settings, aiding intervention personalization. The tutorial offers a resource for researchers interested in using RICLPM for more robust longitudinal analyses of behavioral intervention outcomes.

Indexed as

Cognitive Behavioral TherapyModels, StatisticalOutcome Assessment, Health CareHumansLongitudinal StudiesTreatment OutcomeLongitudinal modelRandom-intercept cross-lagged panel modelTransdiagnostic cognitive-behavioral therapyTreatment mechanismsUnified protocolWithin-person dynamics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.